Browsing by Author "Willer, CJ"
Now showing items 1-20 of 30
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Defining the role of common variation in the genomic and biological architecture of adult human height
Wood, AR; Esko, T; Yang, J; Vedantam, S; Pers, TH; Gustafsson, S; Chun, AY; Estrada, K; Luan, J; Kutalik, Z (2014-11) -
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
Aragam, KG; Jiang, T; Goel, A; Kanoni, S; Wolford, BN; Atri, DS; Weeks, EM; Wang, M; Hindy, G; Zhou, W (2022) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2020) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (vol 52, pg 1314, 2020)
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2021) -
Exome-wide association study of plasma lipids in > 300,000 individuals
Liu, DJ; Peloso, GM; Yu, H; Butterworth, AS; Wang, X; Mahajan, A; Saleheen, D; Emdin, C; Alam, D; Alves, AC (2017-12) -
Genetic studies of body mass index yield new insights for obesity biology
Locke, AE; Kahali, B; Berndt, SI; Justice, AE; Pers, TH; Day, FR; Powell, C; Vedantam, S; Buchkovich, ML; Yang, J (2015-02-12) -
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Ehret, GB; Ferreira, T; Chasman, DI; Jackson, AU; Schmidt, EM; Johnson, T; Thorleifsson, G; Luan, J; Donnelly, LA; Kanoni, S (2016-10) -
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
Lindgren, CM; Heid, IM; Randall, JC; Lamina, C; Steinthorsdottir, V; Qi, L; Speliotes, EK; Thorleifsson, G; Willer, CJ; Herrera, BM (2009-06) -
Genome-wide association study of cardiac troponin I in the general population.
Moksnes, MR; Røsjø, H; Richmond, A; Lyngbakken, MN; Graham, SE; Hansen, AF; Wolford, BN; Gagliano Taliun, SA; LeFaive, J; Rasheed, H (2021-05-07)Circulating cardiac troponin proteins are associated with structural heart disease and predict incident cardiovascular disease in the general population. However, the genetic contribution to cardiac troponin I (cTnI) ... -
Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk.
Brænne, I; Zeng, L; Willenborg, C; Tragante, V; Kessler, T; CARDIoGRAM Consortium; CARDIoGRAMplusC4D Consortium; Willer, CJ; Laakso, M; Wallentin, L (2017)Glatiramer acetate is used therapeutically in multiple sclerosis but also known for adverse effects including elevated coronary artery disease (CAD) risk. The mechanisms underlying the cardiovascular side effects of the ... -
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.
Zhou, W; Kanai, M; Wu, K-HH; Rasheed, H; Tsuo, K; Hirbo, JB; Wang, Y; Bhattacharya, A; Zhao, H; Namba, S (2022-10-12)Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry. ... -
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Kanoni, S; Graham, SE; Wang, Y; Surakka, I; Ramdas, S; Zhu, X; Clarke, SL; Bhatti, KF; Vedantam, S; Winkler, TW (2022) -
Mapping the human genetic architecture of COVID-19
Niemi, MEK; Karjalainen, J; Daly, M; Ganna, A; Mehtonen, J; Cordioli, M; Kaunisto, M; Pigazzini, S; Donner, K; Kivinen, K (2021) -
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Ramdas, S; Judd, J; Graham, SE; Kanoni, S; Wang, Y; Surakka, I; Wenz, B; Clarke, SL; Chesi, A; Wells, A (2022) -
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.
Sterenborg, RBTM; Steinbrenner, I; Li, Y; Bujnis, MN; Naito, T; Marouli, E; Galesloot, TE; Babajide, O; Andreasen, L; Astrup, A (Nature Research, 2024-01-30)To date only a fraction of the genetic footprint of thyroid function has been clarified. We report a genome-wide association study meta-analysis of thyroid function in up to 271,040 individuals of European ancestry, including ... -
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
Kraja, AT; Cook, JP; Warren, HR; Surendran, P; Liu, C; Evangelou, E; Manning, AK; Grarup, N; Drenos, F; Sim, X (American Heart Association, 2017-10-13)Background— Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants ... -
New genetic loci link adipose and insulin biology to body fat distribution
Shungin, D; Winkler, TW; Croteau-Chonka, DC; Ferreira, T; Lockes, AE; Maegi, R; Strawbridge, RJ; Pers, TH; Fischer, K; Justice, AE (2015-02-12) -
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Lu, Y; Day, FR; Gustafsson, S; Buchkovich, ML; Na, J; Bataille, V; Cousminer, DL; Dastani, Z; Drong, AW; Esko, T (2016-02) -
The power of genetic diversity in genome-wide association studies of lipids
Graham, SE; Clarke, SL; Wu, K-HH; Kanoni, S; Zajac, GJM; Ramdas, S; Surakka, I; Ntalla, I; Vedantam, S; Winkler, TW (2021) -
The power of genetic diversity in genome-wide association studies of lipids (vol 600, pg 675, 2021)
Graham, SE; Clarke, SL; Wu, K-HH; Kanoni, S; Zajac, GJM; Ramdas, S; Surakka, I; Ntalla, I; Vedantam, S; Winkler, TW (2023)