Browsing by Author "Guo, M"
Now showing items 1-6 of 6
-
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; Arozena, AA; Adachi, H; Adams, CM; Adams, PD; Adeli, K (2016) -
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky, DJ; Abdel-Aziz, AK; Abdelfatah, S; Abdellatif, M; Abdoli, A; Abel, S; Abeliovich, H; Abildgaard, MH; Abudu, YP; Acevedo-Arozena, A (2021-02-08)In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant ... -
MAFA missense mutation causes familial insulinomatosis and diabetes mellitus.
Iacovazzo, D; Flanagan, SE; Walker, E; Quezado, R; de Sousa Barros, FA; Caswell, R; Johnson, MB; Wakeling, M; Brändle, M; Guo, M (2018-01-30)The β-cell-enriched MAFA transcription factor plays a central role in regulating glucose-stimulated insulin secretion while also demonstrating oncogenic transformation potential in vitro. No disease-causing MAFA variants ... -
A missense mutation in the islet-enriched transcription factor MAFA leads to familial insulinomatosis and diabetes
Iacovazzo, D; Flanagan, SE; Walker, E; Caswell, R; Brandle, M; Johnson, M; Wakeling, M; Guo, M; Dang, MN; Gabrovska, P -
Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males.
Walker, EM; Cha, J; Tong, X; Guo, M; Liu, J-H; Yu, S; Iacovazzo, D; Mauvais-Jarvis, F; Flanagan, SE; Korbonits, M (2021-10-12)A heterozygous missense mutation of the islet β cell-enriched MAFA transcription factor (p.Ser64Phe [S64F]) is found in patients with adult-onset β cell dysfunction (diabetes or insulinomatosis), with men more prone to ... -
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Muus, C; Luecken, MD; Eraslan, G; Sikkema, L; Waghray, A; Heimberg, G; Kobayashi, Y; Vaishnav, ED; Subramanian, A; Smillie, C (2021-03)Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular entry, and their expression may shed light on viral ...