Institute of Dentistry: Recent submissions
Now showing items 821-840 of 1450
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Genetic regulation of mouse glycosylphosphatidylinositol-phospholipase D
(Elsevier, 2004-04-23)Glycosylphosphatidylinositol phospholipase D (GPI-PLD) has been proposed to be responsible for cleaving membrane-associated glycosylphosphatidyl inositol (GPI) molecules to generate inositol phosphoglycan (IPGs), which ... -
Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis
(National Academy of Sciences, 2008-12-09)The ultimate goal for the treatment of autoimmunity is to restore immunological tolerance. Regulatory T cells (Treg) play a central role in immune tolerance, and Treg functional abnormalities have been identified in different ... -
The effect of temperature and ionic solutes on the fluoride release and recharge of glass-ionomer cements.
(Elsevier, 2019-11)OBJECTIVE: To determine the effect of storage temperature and the presence of sodium chloride in solution on the fluoride uptake and release of glass-ionomer cements. METHODS: Several commercial brands were used, and stored ... -
CD19(+)CD24(hi)CD38(hi) B Cells Maintain Regulatory T Cells While Limiting T(H)1 and T(H)17 Differentiation
(American Association for the Advancement of Science, 2013-02-20)The relevance of regulatory B cells in the maintenance of tolerance in healthy individuals or in patients with immune disorders remains understudied. In healthy individuals, CD19+ CD24hiCD38hi B cells suppress CD4+ CD25− ... -
Lipid rafts in T cell signalling and disease
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Protein Phosphorylation and Kinome Profiling Reveal Altered Regulation of Multiple Signaling Pathways in B Lymphocytes From Patients With Systemic Lupus Erythematosus
(Wiley Online, 2010-08-03)Objective The cause of B lymphocyte hyperactivity and autoantibody production in systemic lupus erythematosus (SLE) remains unclear. Previously, we identified abnormalities in the level and translocation of signaling ... -
Pleiotropic Role and Bidirectional Immunomodulation of Innate Lymphoid Cells in Cancer.
(2019)Innate lymphoid cells (ILCs) are largely tissue resident and respond rapidly toward the environmental signals from surrounding tissues and other immune cells. The pleiotropic function of ILCs in diverse contexts underpins ... -
What factors predict the uptake of orthodontic treatment among adults?
(Mosby Inc, 2015-05-30)Introduction Our aim was to evaluate the factors that predict orthodontic treatment uptake among adults attending a specialist practice. Methods A cross-sectional controlled design was adopted in a private practice ... -
Child Caries Management: A Randomized Controlled Trial in Dental Practice
(Sage Publications, 2019-11-26)This multicenter 3-arm, parallel-group, patient-randomized controlled trial compared clinical effectiveness of 3 treatment strategies over 3 y for managing dental caries in primary teeth in UK primary dental care. Participants ...