Search
Now showing items 1-6 of 6
The relationship of human chorionic gonadotropin beta (hCGβ) expression and luteinizing hormone gene mutation (vLH) with prostate cancer in population groups of multi-ethnic origin
(2007)
Data have shown that Black men have the highest incidence and mortality from prostate cancer in the world. Even after adjusting for stage at diagnosis, black men have higher mortality rates than white men (Freedland, 2005). ...
Transcription Factor AP-2 Regulatory Signatures in Breast Cancer
(2007)
AP-2 transcription factors are highly conserved basic helix-span-helix proteins whose
members ((x, ß, y, S and c) are crucial regulators of bryonic development. They also
play an important role in human neoplasia. uohis ...
Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems
(2007)
Embryonic development is regulated by a number of signalling pathways, Which are
critical for normal growth. Many of these genes then continue to play an important role
in the regulation of cell growth and differentiation ...
Pharmacokinetic studies for the development of transdermal drug delivery systems
(2007)
This thesis mainly describes a series of Phase I pharmacokinetic studies conducted on
the TDS®d elivery systemw hich combinedw ith lidocaine,t estosteronea, nd a new drug,
Melanotan-I for the transdermal drug delivery. ...
Interleukin-1[Alpha] production in periodontal disease: the interaction of bacteria and gene polymorphisms.
(2007)
There is good evidence that interleukin-I alpha (IL-Ia) plays a key role in both the host
response to bacteria and the tissue destruction associated with periodontal disease. This
thesis investigated the interaction of ...
Bone marrow derived cells as endothelial precursors and the role of multi-potent progenitor cells in repairing ischaemic tissues.
(2007)
Introduction: Atherosclerosis and its complications are a major cause of death and
disability and it remains a major challenge to develop new therapies for patients with
irreversible end organ damage and ongoing ischaemia. ...