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Epidemiology of septo-optic dysplasia with focus on prevalence and maternal age - A EUROCAT study.
(2018-09)
Septo-optic nerve dysplasia is a rare congenital anomaly with optic nerve hypoplasia, pituitary hormone deficiencies and midline developmental defects of the brain. The clinical findings are visual impairment, hypopituitarism ...
Prevalence of valproate syndrome in Europe from 2005 to 2014: A registry based multi-centre study.
(2018-09)
Women with epilepsy need to continue to take anticonvulsants during their pregnancies to prevent seizures from occurring. Since the 1980's, it has been known that the use of valproate (an anticonvulsant) in the first ...
EUROmediCAT signal detection: a systematic method for identifying potential teratogenic medication.
(2016-10)
AIMS: Information about medication safety in pregnancy is inadequate. We aimed to develop a signal detection methodology to routinely identify unusual associations between medications and congenital anomalies using data ...