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Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure.
(2003-12-31)
BACKGROUND: The design of appropriate strategies to analyze and interpret linkage results for complex human diseases constitutes a challenge. Parameters such as power, definition of phenotype, and replicability have to be ...
Familial loading in specific language impairment: patterns of differences across proband characteristics, gender and relative type.
(2007-04)
There is now little doubt that both environmental factors and genes are likely to make important contributions to the aetiology of specific language impairment (SLI). The most commonly proposed model for understanding these ...
A flexible model for multivariate interval-censored survival times with complex correlation structure.
(2007-02-10)
We focus on the analysis of multivariate survival times with highly structured interdependency and subject to interval censoring. Such data are common in developmental genetics and genetic epidemiology. We propose a flexible ...