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Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety.
(2017-11)
OBJECTIVE: Genetic studies in obese rodents and humans can provide novel insights into the mechanisms involved in energy homeostasis. METHODS: In this study, we genetically mapped the chromosomal region underlying the ...
Transcriptomics of the Prader-Willi syndrome hypothalamus.
(2021)
Prader-Willi syndrome (PWS) is a complex neurodevelopmental disorder, arising from a loss of paternity expressed genetic material on the imprinted chromosome locus 15q11-q13. Despite increasing clarity on the underlying ...