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Now showing items 1-10 of 15
What cervical screening is appropriate for women who have been vaccinated against high risk HPV? A simulation study.
(2018-02-15)
Women vaccinated against HPV16/18 are approaching the age for cervical screening; however, an updated screening algorithm has not been agreed. We use a microsimulation model calibrated to real published data to determine ...
Impact of a decision aid about stratified ovarian cancer risk-management on women's knowledge and intentions: a randomised online experimental survey study.
(2017-11-16)
BACKGROUND: Risk stratification using genetic and other types of personal information could improve current best available approaches to ovarian cancer risk reduction, improving identification of women at increased risk ...
Human papilloma virus genotyping for the cross-sectional and longitudinal probability of developing cervical intraepithelial neoplasia grade 2 or more.
(2018-07-15)
Human papilloma virus (HPV) testing is more sensitive but less specific than cytology. We evaluated stand-alone genotyping as a possible triage method. During a multicentre randomised controlled trial comparing HPV testing ...
Breast cancer risk in a screening cohort of Asian and white British/Irish women from Manchester UK.
(2018-01-25)
BACKGROUND: The differences between breast cancer risk factors in white British/Irish and Asian women attending screening in the UK are not well documented. METHODS: Between 2009-15 ethnicity and traditional breast cancer ...
Prediction of cervical cancer incidence in England, UK, up to 2040, under four scenarios: a modelling study.
(2018-01)
BACKGROUND: In the next 25 years, the epidemiology of cervical cancer in England, UK, will change: human papillomavirus (HPV) screening will be the primary test for cervical cancer. Additionally, the proportion of women ...
Effect of Mammography Screening on Mortality by Histological Grade.
(American Association for Cancer Research, 2017-11-17)
Background: It has been asserted that mammography screening preferentially benefits those with less aggressive cancers, with lesser or no impact on more rapidly progressing and therefore more life-threatening tumors.Methods: ...
The effect of optimised patient information materials on recruitment in a lung cancer screening trial: an embedded randomised recruitment trial.
(2018-09-18)
BACKGROUND: Written participant information materials are important for ensuring that potential trial participants receive necessary information so that they can provide informed consent. However, such materials are ...
Long-Term Secondary Care Costs of Endometrial Cancer: A Prospective Cohort Study Nested within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
(2016)
BACKGROUND: There is limited evidence on the costs of Endometrial Cancer (EC) by stage of disease. We estimated the long-term secondary care costs of EC according to stage at diagnosis in an English population-based cohort. ...
Need for expanded HPV genotyping for cervical screening.
(2016-12)
The focus for HPV genotyping has largely been on types 16 and 18, based on their high prevalence in cervix cancer. However screening is focussed on the detection of high grade precursor lesions (CIN3 and CIN2), where other ...
Cancer screening in Australia: future directions in melanoma, Lynch syndrome, and liver, lung and prostate cancers.
(2019-07-31)
While Australia now has well-established national screening programs for breast, bowel and cervical cancers, research continues into the feasibility of developing systematic screening programs for a number of other cancers. ...