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ABCB1 Does Not Require the Side-Chain Hydrogen-Bond Donors Gln347, Gln725, Gln990 to Confer Cellular Resistance to the Anticancer Drug Taxol
(MDPI, 2021-08-09)
The multidrug efflux transporter ABCB1 is clinically important for drug absorption and
distribution and can be a determinant of chemotherapy failure. Recent structure data shows that three
glutamines donate hydrogen bonds ...