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Now showing items 41-50 of 72
Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews.
(2023-06-08)
BACKGROUND: Following hip fracture, people sustain an acute blood loss caused by the injury and subsequent surgery. Because the majority of hip fractures occur in older adults, blood loss may be compounded by pre-existing ...
Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial.
(2022-10-08)
BACKGROUND: Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous studies have shown that allopurinol has positive effects on several cardiovascular parameters. The ALL-HEART study aimed to ...
Can ancient and modern stressors be distinguished? A mixed-methods exploration of psychosocial characteristics and health symptoms in young and older adults.
(2022-03)
A novel conceptualisation of stress includes a distinction between ancient (AS) and modern stressors (MS); the notion that established adaptive psychophysiological coping processes may enable individuals to better withstand ...
Use of repurposed and adjuvant drugs in hospital patients with covid-19: multinational network cohort study.
(2021-05-11)
OBJECTIVE: To investigate the use of repurposed and adjuvant drugs in patients admitted to hospital with covid-19 across three continents. DESIGN: Multinational network cohort study. SETTING: Hospital electronic health ...
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
(2021-03)
Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular entry, and their expression may shed light on viral ...
Epidemiology & management of complex ankle fractures in the United Kingdom: A multicentre cohort study.
(2024-02)
BACKGROUND: Patient factors are known to contribute to decision making and treatment of ankle fractures. The presence of poor baseline mobility, diabetes, neuropathy, alcoholism, cognitive impairment, inflammatory arthritis ...
Exploring three levels of interoception in people with functional motor disorders.
(2021-05)
INTRODUCTION: A three-level model of interoception has recently been defined. We aim to study the interoceptive processing in individuals with functional motor disorder (FMD). METHODS: Twenty-two patients with FMD were ...
Living with polypharmacy: a narrative interview study with older Pakistanis in East London.
(2023-11-15)
BACKGROUND: Polypharmacy is a growing and major public health issue. It can be burdensome and risky for patients and costly to healthcare systems. Older adults and those from ethnic minority backgrounds are disproportionately ...
Functional dentition and changes in dietary patterns among older adults in Thailand.
(2021-10)
OBJECTIVE: To investigate the relationship between functional dentition (FD) and changes in dietary patterns (DP) in older adults. DESIGN: This was a 12-month prospective study, with dental examinations at baseline and ...