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Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.
(2015-03-04)
An increasingly powerful approach for studying brain circuits relies on targeting genetically encoded sensors and effectors to specific cell types. However, current approaches for this are still limited in functionality ...
Restoration of vision after transplantation of photoreceptors.
(2012-05-03)
Cell transplantation is a potential strategy for treating blindness caused by the loss of photoreceptors. Although transplanted rod-precursor cells are able to migrate into the adult retina and differentiate to acquire the ...
Adaptation maintains population homeostasis in primary visual cortex.
(2013-06)
Sensory systems exhibit mechanisms of neural adaptation, which adjust neuronal activity on the basis of recent stimulus history. In primary visual cortex (V1) in particular, adaptation controls the responsiveness of ...
Myostatin dysfunction does not protect from fasting-induced loss of muscle mass in mice.
(2019-09-01)
OBJECTIVES: The aim of the study was to investigate if myostatin dysfunction can ameliorate fasting-induced muscle wasting. METHODS: 18-week old males from Berlin high (BEH) strain with myostatin dysfunction and wild type ...