Browsing by Subject "B cells"
Now showing items 1-20 of 21
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B cells defined by immunoglobulin isotypes
(Oxford University Press, 2022-10-05) -
B cells in pancreatic cancer stroma
(2022) -
Circulating and intrahepatic antiviral B cells are defective in hepatitis B.
(American Society for Clinical Investigation, 2018-08-09)B cells are increasingly recognized as playing an important role in the ongoing control of hepatitis B virus (HBV). The development of antibodies against the viral surface antigen (HBV surface antigen [HBsAgs]) constitutes ... -
Discrepancies in the Tumor Microenvironment of Spontaneous and Orthotopic Murine Models of Pancreatic Cancer Uncover a New Immunostimulatory Phenotype for B Cells.
(2019)B cells are salient features of pancreatic ductal adenocarcinoma (PDAC) tumors, yet their role in this disease remains controversial. Murine studies have indicated a protumoral role for B cells, whereas clinical data show ... -
Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy.
(2018-03)OBJECTIVES: To compare the effects of rituximab versus placebo on salivary gland ultrasound (SGUS) in primary Sjögren's syndrome (PSS) in a multicentre, multiobserver phase III trial substudy. METHODS: Subjects consenting ... -
PD-1 blockade partially recovers dysfunctional virus-specific B cells in chronic hepatitis B infection.
(2018-10-01)Chronic HBV (CHB) infection suppresses virus-specific T cells, but its impact on humoral immunity has been poorly analyzed. Here, we developed a dual-staining method that utilizes hepatitis B virus (HBV) surface antigens ... -
Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease.
(Wiley, 2024-04-29)Single cell RNA sequencing of human full thickness Crohn's disease (CD) small bowel resection specimens was used to identify potential therapeutic targets for stricturing (S) CD. Using an unbiased approach, 16 cell lineages ...