Browsing by Author "Zaborsky, N"
Now showing items 1-3 of 3
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CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.
Gutjahr, JC; Bayer, E; Yu, X; Laufer, JM; Höpner, JP; Tesanovic, S; Härzschel, A; Auer, G; Rieß, T; Salmhofer, A (Ferrata Storti Foundation, 2020-07-02)Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone ... -
TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia
Szenes, E; Haerzschel, A; Decker, S; Tissino, E; Pischeli, J; Gutjahr, JC; Kissel, S; Pennisi, S; Hoepner, JP; Egle, A (Springer Nature, 2020-02-21) -
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia
Catakovic, K; Gassner, FJ; Ratswohl, C; Zaborsky, N; Rebhandl, S; Schubert, M; Steiner, M; Gutjahr, JC; Pleyer, L; Egle, A (Taylor & Francis, 2017-09-21)While research on T cell exhaustion in context of cancer particularly focuses on CD8C cytotoxic T cells, the role of inhibitory receptors on CD4C T-helper cells have remained largely unexplored. TIGIT is a recently identified ...