Browsing by Author "Turtle, L"

Now showing items 1-4 of 4

    • Accelarated immune ageing is associated with COVID-19 disease severity. 

      Lord, JM; Veenith, T; Sullivan, J; Sharma-Oates, A; Richter, AG; Greening, NJ; McAuley, HJC; Evans, RA; Moss, P; Moore, SC (2024-01-11)
      BACKGROUND: The striking increase in COVID-19 severity in older adults provides a clear example of immunesenescence, the age-related remodelling of the immune system. To better characterise the association between convalescent ...

    • Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study 

      Elneima, O; McAuley, HJC; Leavy, OC; Chalmers, JD; Horsley, A; Ho, L-P; Marks, M; Poinasamy, K; Raman, B; Shikotra, A

    • Genetic mechanisms of critical illness in Covid-19. 

      Pairo-Castineira, E; Clohisey, S; Klaric, L; Bretherick, AD; Rawlik, K; Pasko, D; Walker, S; Parkinson, N; Fourman, MH; Russell, CD (2020-12-11)
      Host-mediated lung inflammation is present,1 and drives mortality,2 in critical illness caused by Covid-19. Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development.3 ...

    • Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease. 

      Liew, F; Efstathiou, C; Fontanella, S; Richardson, M; Saunders, R; Swieboda, D; Sidhu, JK; Ascough, S; Moore, SC; Mohamed, N (Springer Nature, 2024-04-08)
      One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood1. Here we profiled 368 ...