Browsing by Author "Gygi, SP"

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    • FUS-SMN protein interactions link the motor neuron diseases ALS and SMA 

      Yamazaki, T; Chen, S; Yu, Y; Yan, B; Haertlein, TC; Carrasco, MA; Tapia, JC; Zhai, B; Das, R; Lalancette-Hebert, M (Cell Press, 2012-09-27)
      Mutations in the RNA binding protein FUS cause amyotrophic lateral sclerosis (ALS), a fatal adult motor neuron disease. Decreased expression of SMN causes the fatal childhood motor neuron disorder spinal muscular atrophy ...