Browsing by Author "Gupta, B"
Now showing items 1-6 of 6
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Age-associated mitochondrial DNA mutations cause metabolic remodelling that contributes to accelerated intestinal tumorigenesis.
Smith, AL; Whitehall, JC; Bradshaw, C; Gay, D; Robertson, F; Blain, AP; Hudson, G; Pyle, A; Houghton, D; Hunt, M (2020-10)Oxidative phosphorylation (OXPHOS) defects caused by somatic mitochondrial DNA (mtDNA) mutations increase with age in human colorectal epithelium and are prevalent in colorectal tumours, but whether they actively contribute ... -
Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 A Systematic Analysis for the Global Burden of Disease Study 2019
Kocarnik, JM; Compton, K; Dean, FE; Fu, W; Gaw, BL; Harvey, JD; Henrikson, HJ; Lu, D; Pennini, A; Xu, R (2022) -
Eligibility for antiamyloid treatment: preparing for disease-modifying therapies for Alzheimer's disease.
Dobson, R; Patterson, K; Malik, R; Mandal, U; Asif, H; Humphreys, R; Payne, M; O-Charoenrat, E; Huzzey, L; Clare, A (BMJ Publishing Group, 2024-06-11)BACKGROUND: Disease-modifying therapies (DMTs) for Alzheimer's disease (AD) have early evidence of efficacy. Widespread delivery of DMTs will require major service reconfiguration. Treatment pathways will need to include ... -
The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019
Khanh, BT; Lang, JJ; Compton, K; Xu, R; Acheson, AR; Henrikson, HJ; Kocarnik, JM; Penberthy, L; Aali, A; Abbas, Q (2022) -
The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories A Systematic Analysis for the Global Burden of Disease Study 2019
da Cunha, AR; Compton, K; Xu, R; Mishra, R; Drangsholt, MT; Antunes, JLF; Kerr, AR; Acheson, AR; Lu, D; Wallace, LE (2023) -
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019
Reitsma, MB; Reitsma, MB; Kendrick, PJ; Ababneh, E; Abbafati, C; Abbasi-Kangevari, M; Abdoli, A; Abedi, A; Abhilash, ES; Abila, DB (Elsevier, 2021-05-27)