Browsing by Author "Gambaro, G"
Now showing items 1-14 of 14
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Directional dominance on stature and cognition in diverse human populations
Joshi, PK; Esko, T; Mattsson, H; Eklund, N; Gandin, I; Nutile, T; Jackson, AU; Schurmann, C; Smith, AV; Zhang, W (2015-07-23) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2020) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (vol 52, pg 1314, 2020)
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2021) -
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Pattaro, C; Teumer, A; Gorski, M; Chu, AY; Li, M; Mijatovic, V; Garnaas, M; Tin, A; Sorice, R; Li, Y (2016-01) -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Lee, PH; Anttila, V; Won, H; Feng, Y-CA; Rosenthal, J; Zhu, Z; Tucker-Drob, EM; Nivard, MG; Grotzinger, AD; Posthuma, D (2019-12-12) -
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Wessel, J; Chu, AY; Willems, SM; Wang, S; Yaghootkar, H; Brody, JA; Dauriz, M; Hivert, M-F; Raghavan, S; Lipovich, L (2015-01) -
Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans
Huffman, JE; Albrecht, E; Teumer, A; Mangino, M; Kapur, K; Johnson, T; Kutalik, Z; Pirastu, N; Pistis, G; Lopez, LM (2015-03-26) -
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
Kraja, AT; Cook, JP; Warren, HR; Surendran, P; Liu, C; Evangelou, E; Manning, AK; Grarup, N; Drenos, F; Sim, X (American Heart Association, 2017-10-13)Background— Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants ... -
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Mahajan, A; Wessel, J; Willems, SM; Zhao, W; Robertson, NR; Chu, AY; Gan, W; Kitajima, H; Taliun, D; Rayner, NW (Nature Research (part of Springer Nature), 2018-04-09)We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls of diverse ancestry, identifying 40 coding variant association signals (P < 2.2 × 10−7); of these, 16 map outside known risk-associated ... -
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
Li, M; Li, Y; Weeks, O; Mijatovic, V; Teumer, A; Huffman, JE; Tromp, G; Fuchsberger, C; Gorski, M; Lyytikäinen, L-P (2017-03)Genome-wide association studies have identified >50 common variants associated with kidney function, but these variants do not fully explain the variation in eGFR. We performed a two-stage meta-analysis of associations ... -
Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis
Yang, Y; van der Klaauw, AA; Zhu, L; Cacciottolo, TM; He, Y; Stadler, LKJ; Wang, C; Xu, P; Saito, K; Hinton, A (2019-04-12) -
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Surendran, P; Drenos, F; Young, R; Warren, H; Cook, JP; Manning, AK; Grarup, N; Sim, X; Barnes, DR; Witkowska, K (2016-10) -
The UK10K project identifies rare variants in health and disease
Walter, K; Min, JL; Huang, J; Crooks, L; Memari, Y; McCarthy, S; Perry, JRB; Xu, C; Futema, M; Lawson, D (2015-10-01) -
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits
Tachmazidou, I; Suveges, D; Min, JL; Ritchie, GRS; Steinberg, J; Walter, K; Iotchkova, V; Schwartzentruber, J; Huang, J; Memari, Y (2017-06-01)