Browsing by Author "Fantin, A"
Now showing items 1-5 of 5
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HS6ST1 Insufficiency Causes Self-Limited Delayed Puberty in Contrast With Other GnRH Deficiency Genes.
Howard, SR; Oleari, R; Poliandri, A; Chantzara, V; Fantin, A; Ruiz-Babot, G; Metherell, LA; Cabrera, CP; Barnes, MR; Wehkalampi, K (2018-09-01)Context: Self-limited delayed puberty (DP) segregates in an autosomal-dominant pattern, but the genetic basis is largely unknown. Although DP is sometimes seen in relatives of patients with hypogonadotropic hypogonadism ... -
Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells
Raimondi, C; Fantin, A; Lampropoulou, A; Denti, L; Chikh, A; Ruhrberg, C (Rockefeller University Press, 2014-06-02) -
SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability.
Lettieri, A; Oleari, R; van den Munkhof, MH; van Battum, EY; Verhagen, MG; Tacconi, C; Spreafico, M; Paganoni, AJJ; Azzarelli, R; Andre', V (Nature Research, 2023-12-07)Innervation of the hypothalamic median eminence by Gonadotropin-Releasing Hormone (GnRH) neurons is vital to ensure puberty onset and successful reproduction. However, the molecular and cellular mechanisms underlying median ... -
A Small Molecule Inhibitor of PDK1/PLC gamma 1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion
Raimondi, C; Calleja, V; Ferro, R; Fantin, A; Riley, AM; Potter, BVL; Brennan, CH; Maffucci, T; Larijani, B; Falasca, M (2016-05-20) -
VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation.
Fantin, A; Lampropoulou, A; Senatore, V; Brash, JT; Prahst, C; Lange, CA; Liyanage, SE; Raimondi, C; Bainbridge, JW; Augustin, HG (2017-04-03)The vascular endothelial growth factor (VEGF) isoform VEGF165 stimulates vascular growth and hyperpermeability. Whereas blood vessel growth is essential to sustain organ health, chronic hyperpermeability causes damaging ...