Browsing by Author "Evangelou, E"
Now showing items 1-20 of 37
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Association analyses based on false discovery rate implicate new loci for coronary artery disease
Nelson, CP; Goel, A; Butterworth, AS; Kanoni, S; Webb, TR; Marouli, E; Zeng, L; Ntalla, I; Lai, FY; Hopewell, JC (2017-09) -
Associations of autozygosity with a broad range of human phenotypes
Clark, DW; Okada, Y; Moore, KHS; Mason, D; Pirastu, N; Gandin, I; Mattsson, H; Barnes, CLK; Lin, K; Zhao, JH (2019-10-31) -
Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Warren, HR; Evangelou, E; Cabrera, CP; Gao, H; Ren, M; Mifsud, B; Ntalla, I; Surendran, P; Liu, C; Cook, JP (2017-09-27) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2020) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (vol 52, pg 1314, 2020)
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2021) -
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use
Brazel, DM; Jiang, Y; Hughey, JM; Turcot, V; Zhan, X; Gong, J; Batini, C; Weissenkampen, JD; Liu, M; Barnes, DR (2019-06-01) -
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
de Las Fuentes, L; Sung, YJ; Noordam, R; Winkler, T; Feitosa, MF; Schwander, K; Bentley, AR; Brown, MR; Guo, X; Manning, A (Springer Nature, 2020-05-05)Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses ... -
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Evangelou, E; Warren, HR; Mosen-Ansorena, D; Mifsu, B; Pazoki, R; Gao, H; Ntritsos, G; Dimou, N; Cabrer, CP; Karaman, I (2018-10) -
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Ehret, GB; Ferreira, T; Chasman, DI; Jackson, AU; Schmidt, EM; Johnson, T; Thorleifsson, G; Luan, J; Donnelly, LA; Kanoni, S (2016-10) -
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (vol 49, pg 403, 2017)
Warren, HR; Evangelou, E; Cabrera, CP; Gao, H; Ren, M; Mifsud, B; Ntalla, I; Surendran, P; Liu, C; Cook, JP (2017-10) -
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos
Sofer, T; Wong, Q; Hartwig, FP; Taylor, K; Warren, HR; Evangelou, E; Cabrera, CP; Levy, D; Kramer, H; Lange, LA (2017-09-04) -
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study
Prins, BP; Abbasi, A; Wong, A; Vaez, A; Nolte, I; Franceschini, N; Stuart, PE; Achury, JG; Mistry, V; Bradfield, JP (2016-06) -
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Sung, YJ; Winkler, TW; de las Fuentes, L; Bentley, AR; Brown, MR; Kraja, AT; Schwander, K; Ntalla, I; Guo, X; Franceschini, N (2018-03-01) -
Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease
Marouli, E; Del Greco, MF; Astley, CM; Yang, J; Ahmad, S; Berndt, SI; Caulfield, MJ; Evangelou, E; McKnight, B; Medina-Gomez, C (2019-03-27) -
Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease.
Marouli, E; Del Greco, MF; Astley, CM; Yang, J; Ahmad, S; Berndt, SI; Caulfield, MJ; Evangelou, E; McKnight, B; Medina-Gomez, C (2019-03-27)There is evidence that lower height is associated with a higher risk of coronary artery disease (CAD) and increased risk of type 2 diabetes (T2D). It is not clear though whether these associations are causal, direct or ... -
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Erzurumluoglu, AM; Liu, M; Jackson, VE; Barnes, DR; Datta, G; Melbourne, CA; Young, R; Batini, C; Surendran, P; Jiang, T (Springer Nature, 2019-01-07)Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking ... -
Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
de Vries, PS; Brown, MR; Bentley, AR; Sung, YJ; Winkler, TW; Ntalla, I; Schwander, K; Kraja, AT; Guo, X; Franceschini, N (Oxford University Press, 2019-01-29)An individual's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-alcohol interactions ... -
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, AR; Sung, YJ; Brown, MR; Winkler, TW; Kraja, AT; Ntalla, I; Schwander, K; Chasman, DI; Lim, E; Deng, X (Nature Research (part of Springer Nature), 2019-03-29)The concentrations of high- and low-density-lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conducted a ... -
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Sung, YJ; de Las Fuentes, L; Winkler, TW; Chasman, DI; Bentley, AR; Kraja, AT; Ntalla, I; Warren, HR; Guo, X; Schwander, K (2019-08-01) -
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
Noordam, R; Bos, MM; Wang, H; Winkler, TW; Bentley, AR; Kilpelainen, TO; de Vries, PS; Sung, YJ; Schwander, K; Cade, BE (Nature Research (part of Springer Nature), 2019-11-12)Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ancestry genome-wide ...