Browsing by Author "Dunning, AM"
Now showing items 1-14 of 14
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Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants
Wang, A; Shen, J; Rodriguez, AA; Saunders, EJ; Chen, F; Janivara, R; Darst, BF; Sheng, X; Xu, Y; Chou, AJ (Nature Research, 2023-11-09)The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry ... -
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use
Brazel, DM; Jiang, Y; Hughey, JM; Turcot, V; Zhan, X; Gong, J; Batini, C; Weissenkampen, JD; Liu, M; Barnes, DR (2019-06-01) -
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (vol 9, 1340, 2018)
Vijayakrishnan, J; Studd, J; Broderick, P; Kinnersley, B; Holroyd, A; Law, PJ; Kumar, R; Allan, JM; Harrison, CJ; Moorman, AV (2019-01-21) -
Genome-wide association study of germline variants and breast cancer-specific mortality.
Escala-Garcia, M; Guo, Q; Dörk, T; Canisius, S; Keeman, R; Dennis, J; Beesley, J; Lecarpentier, J; Bolla, MK; Wang, Q (Nature Publishing Group, 2019-02-21)BACKGROUND: We examined the associations between germline variants and breast cancer mortality using a large meta-analysis of women of European ancestry. METHODS: Meta-analyses included summary estimates based on Cox models ... -
Germline variation at 8q24 and prostate cancer risk in men of European ancestry (vol 9, 4616, 2018)
Matejcic, M; Saunders, EJ; Dadaev, T; Brook, MN; Wang, K; Sheng, X; Al Olama, AA; Schumacher, FR; Ingles, SA; Govindasami, K (2019-01-17) -
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Erzurumluoglu, AM; Liu, M; Jackson, VE; Barnes, DR; Datta, G; Melbourne, CA; Young, R; Batini, C; Surendran, P; Jiang, T (Springer Nature, 2019-01-07)Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking ... -
No Association Between Polygenic Risk Scores for Cancer and Development of Radiation Therapy Toxicity
Barnett, GC; Kerns, SL; Dorling, L; Fachal, L; Aguado-Barrera, ME; Martinez-Calvo, L; Jandu, HK; Welsh, C; Tyrer, J; Coles, CE (2022) -
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
Mavaddat, N; Michailidou, K; Dennis, J; Lush, M; Fachal, L; Lee, A; Tyrer, JP; Chen, T-H; Wang, Q; Bolla, MK (2019-01-03) -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2018-01) -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 26, 2017)
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2019-07) -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 26, 2018)
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2018-05) -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 765, 2017)
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2018-05) -
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Justice, AE; Karaderi, T; Highland, HM; Young, KL; Graff, M; Lu, Y; Turcot, V; Auer, PL; Fine, RS; Guo, X (Nature Research (part of Springer Nature), 2019-02-18)Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted ... -
Rare and low-frequency coding variants alter human adult height
Marouli, E; Graff, M; Medina-Gomez, C; Lo, KS; Wood, AR; Kjaer, TR; Fine, RS; Lu, Y; Schurmann, C; Highland, HM (2017-02-09)