Browsing by Author "Gustafsson, S"
Now showing items 21-28 of 28
-
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 765, 2017)
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2018-05) -
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Justice, AE; Karaderi, T; Highland, HM; Young, KL; Graff, M; Lu, Y; Turcot, V; Auer, PL; Fine, RS; Guo, X (Nature Research (part of Springer Nature), 2019-02-18)Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted ... -
Rare and low-frequency coding variants alter human adult height
Marouli, E; Graff, M; Medina-Gomez, C; Lo, KS; Wood, AR; Kjaer, TR; Fine, RS; Lu, Y; Schurmann, C; Highland, HM (2017-02-09) -
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Mahajan, A; Wessel, J; Willems, SM; Zhao, W; Robertson, NR; Chu, AY; Gan, W; Kitajima, H; Taliun, D; Rayner, NW (Nature Research (part of Springer Nature), 2018-04-09)We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls of diverse ancestry, identifying 40 coding variant association signals (P < 2.2 × 10−7); of these, 16 map outside known risk-associated ... -
A saturated map of common genetic variants associated with human height
Yengo, L; Vedantam, S; Marouli, E; Sidorenko, J; Bartell, E; Sakaue, S; Graff, M; Eliasen, AU; Jiang, Y; Raghavan, S (2022) -
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
Randall, JC; Winkler, TW; Kutalik, Z; Berndt, SI; Jackson, AU; Monda, KL; Kilpelaeinen, TO; Esko, T; Maegi, R; Li, S (2013-06) -
Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation
Ng, N; Willems, SM; Fernandez, J; Fine, RS; Wheeler, E; Wessel, J; Kitajima, H; Marenne, G; Rundle, JK; Sim, X (2019-10-15) -
The trans-ancestral genomic architecture of glycemic traits.
Chen, J; Spracklen, CN; Marenne, G; Varshney, A; Corbin, LJ; Luan, J; Willems, SM; Wu, Y; Zhang, X; Horikoshi, M (2021-05-31)Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide ...