Browsing Centre for Neuroscience, Surgery and Trauma by Title
Now showing items 148-167 of 1369
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Botulinum toxin type A for the treatment of dyssynergic defaecation in adults: A systematic review.
(Wiley, 2020-06-11)AIM: Dyssynergic defaecation (DD) is characterised by inappropriate co-ordination of the pelvic floor muscles during defaecation, resulting in impaired stool expulsion. The mainstay of treatment is biofeedback and alternative ... -
The Bouffant Hat Debate and the Illusion of Quality Improvement.
(Lippincott, Williams & Wilkins, 2020-04)In 2015, the Association of Perioperative Registered Nurses (AORN) published guidance aiming to reduce surgical site infection (SSI). One stipulation was that surgeons and other practitioners should wear “bouffant” style ... -
The BRadykinesia Akinesia INcoordination (BRAIN) Tap Test: Capturing the Sequence Effect.
(2019-07)Background: The BRadykinesia Akinesia INcoordination (BRAIN) tap test is an online keyboard tapping task that has been previously validated to assess upper limb motor function in Parkinson's disease (PD). Objectives: To ... -
Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation.
(2014-12-17)Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development ... -
Brain Phospholipid Precursors Administered Post-Injury Reduce Tissue Damage and Improve Neurological Outcome in Experimental Traumatic Brain Injury.
(2019-01-01)Traumatic brain injury (TBI) leads to cellular loss, destabilization of membranes, disruption of synapses and altered brain connectivity, and increased risk of neurodegenerative disease. A significant and long-lasting ... -
The BRAIN test: a keyboard-tapping test to assess disability and clinical features of multiple sclerosis.
(2018-02)BACKGROUND: The BRadykinesia Akinesia INcordination (BRAIN) test is an online keyboard-tapping test previously validated as a sensitive tool for detecting signs of Parkinson's disease. OBJECTIVES: To determine whether the ... -
Brain tumour genetic network signatures of survival
(2023-01-15) -
C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
(Oxford University Press, 2020-09-04) -
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity.
(2018-01-24)Mutations in C9ORF72 are the most common cause of familial amyotrophic lateral sclerosis (ALS). Here, through a combination of RNA-Seq and electrophysiological studies on induced pluripotent stem cell (iPSC)-derived motor ... -
Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells
(National Academy of Sciences, 2017-07-10)Caffeine, generally known as a stimulant of gastric acid secretion (GAS), is a bitter-tasting compound that activates several taste type 2 bitter receptors (TAS2Rs). TAS2Rs are expressed in the mouth and in several extraoral ...