Centre for Neuroscience, Surgery and Trauma
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Neuroscience, Surgery and Trauma research at Barts and The London covers a wide range of topics: general trauma and neurotrauma, neurodegeneration, neuroimmunology, NBRC and Neurogastroenterology.
Recent Submissions
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Thromboprophylaxis for the trauma and orthopaedic surgeon.
(British Editorial Society of Bone and Joint Surgery, 2024-04-01) -
Variation in surgical demand and time to hip fracture repair: a Canadian database study.
(BMC, 2020-10-10)BACKGROUND: Competing demands for operative resources may affect time to hip fracture surgery. We sought to determine the time to hip fracture surgery by variation in demand in Canadian hospitals. METHODS: We obtained ... -
Effectiveness of community-based rehabilitation interventions incorporating outdoor mobility on ambulatory ability and falls-related self-efficacy after hip fracture: a systematic review and meta-analysis.
(2021-06-19)UNLABELLED: There is limited evidence from 11 randomised controlled trials on the effect of rehabilitation interventions which incorporate outdoor mobility on ambulatory ability and/or self-efficacy after hip fracture. ... -
Prognostic factors of depression after hip fracture surgery: Systematic review
(Elsevier, 2022-02) -
Factors affecting mortality after coronary bypass surgery: a scoping review.
(BMC, 2022-03-21)OBJECTIVES: Previous research reports numerous factors of post-operative mortality in patients undergoing isolated coronary artery bypass graft surgery. However, this evidence has not been mapped to the conceptual framework ... -
Trajectories of depressive symptoms among older adults and in adults with hip fracture: Analysis from the English Longitudinal Study of Ageing
(Oxford University Press, 2022-09-08) -
Inequity in exercise-based interventions for adults with intermittent claudication due to peripheral arterial disease: a systematic review.
(Taylor and Francis Group, 2023-08)PURPOSE: To determine the equity in access to trials of exercise interventions for adults with intermittent claudication due to peripheral arterial disease. METHODS: Systematic electronic database searches of MEDLINE, ... -
Perioperative interventions to improve early mobilisation and physical function after hip fracture: a systematic review and meta-analysis.
(Oxford University Press, 2023-08-01)BACKGROUND: Perioperative interventions could enhance early mobilisation and physical function after hip fracture surgery. OBJECTIVE: Determine the effectiveness of perioperative interventions on early mobilisation and ... -
Development and Validation of Multivariable Prediction Models for In-Hospital Death, 30-Day Death, and Change in Residence After Hip Fracture Surgery and the "Stratify-Hip" Algorithm.
(Oxford University Press, 2023-08-09)BACKGROUND: To develop and validate the stratify-hip algorithm (multivariable prediction models to predict those at low, medium, and high risk across in-hospital death, 30-day death, and residence change after hip fracture). ... -
Inequity in exercise-based interventions for adults with rheumatoid arthritis: a systematic review.
(Oxford University Press, 2023-01-24)OBJECTIVES: This systematic review describes the extent to which PROGRESS-Plus equity factors were considered in the eligibility criteria of trials of exercise interventions for adults with RA. METHODS: Electronic databases ... -
Evaluating patient factors, operative management and postoperative outcomes in trauma laparotomy patients worldwide: a protocol for a global observational multicentre trauma study.
(BMJ Publishing Group, 2024-04-05)INTRODUCTION: Trauma contributes to the greatest loss of disability-adjusted life-years for adolescents and young adults worldwide. In the context of global abdominal trauma, the trauma laparotomy is the most commonly ... -
Anorectal function testing
(Elsevier, 2024-03) -
Democratising access to dementia research.
(2024)As the UK population ages, dementia affects an increasing proportion of the population. There is a drive to accelerate dementia research, however access to research is not equitably distributed. We examine access to dementia ... -
Delays in Multiple Sclerosis diagnosis (DIMES): protocol for a multicentre, observational study of multiple sclerosis diagnostic pathways in the United Kingdom and Republic of Ireland.
(2024-03-28)BACKGROUND: Multiple sclerosis (MS) is a leading cause of non-traumatic disability in young adults. Accumulating evidence indicates early diagnosis and early treatment improves long-term outcomes. However, the MS diagnostic ... -
O64: Aortic Trauma in the UK (UK): Vascular Interventions and Surgery in Trauma Audit (VISTA)
(Oxford University Press (OUP), 2024-03-18) -
O65: Extremity Trauma in the UK (UK): Vascular Interventions and Surgery in Trauma Audit (VISTA)
(Oxford University Press (OUP), 2024-03-18) -
The role of depression in the association between mobilisation timing and live discharge after hip fracture surgery: Secondary analysis of the UK National Hip Fracture Database
(Public Library of Science, 2024-04-04)Purpose The aim was to compare the probability of discharge after hip fracture surgery conditional on being alive and in hospital between patients mobilised within and beyond 36-hours of surgery across groups defined by ...