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This is a pre-copyedited, author-produced version of an article accepted for publication in Family Practice, following peer review. The version of record: Natalie Armstrong, Deborah Swinglehurst; Understanding medical overuse: the case of problematic polypharmacy and the potential of ethnography, Family Practice, cmy022, doi: 10.1093/fampra/cmy022 is available online at: https://doi.org/10.1093/fampra/cmy022