Browsing Centre for Environmental and Preventive Medicine (CEPM) by Title
Now showing items 116-135 of 305
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Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts.
(2019-12)BACKGROUND: Several reports have identified different patterns of Parkinson's disease progression in individuals carrying missense variants in GBA or LRRK2 genes. The overall contribution of genetic factors to the severity ... -
Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019 Update From the GBD 2019 Study
(Elsevier, 2020-12-22)Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD ... -
Grapefruit Juice and Statins (Invited Letter in Response to Bailey)
We determined the validity of current medical advice to avoid grapefruit juice consumption while taking 3 widely used statins. A daily glass of grapefruit juice increases blood levels of simvastatin and lovastatin by about ... -
High sodium food consumption pattern among Malaysian population
(BMC part of Springer Nature, 2021-05-31)Background: Sodium is an essential mineral needed by the human body that must be obtained from food. An excess intake, however, can lead to many diseases. As food is the main source of sodium, this study aims to provide ... -
"I'm not strong enough; I'm not good enough. I can't do this, I'm failing"- A qualitative study of low-socioeconomic status smokers' experiences with accesssing cessation support and the role for alternative technology-based support.
(2017-11-13)BACKGROUND: The social gradient in smoking rates persist with an overrepresentation of smoking and its associated harms concentrated within lower socioeconomic status (SES) populations. Low-SES smokers are motivated to ... -
The illusion of polygenic disease risk prediction
(Springer Nature, 2019-01-12) -
The impact of baseline potassium intake on the dose-response relation between sodium reduction and blood pressure change: Systematic review and meta-analysis of randomized trials
(Springer Nature [academic journals on nature.com], 2021-03-05) -
Impact of color-coded and warning nutrition labelling schemes: A systematic review and network meta-analysis.
(Public Library of Science, 2021-10-05)BACKGROUND: Suboptimal diets are a leading risk factor for death and disability. Nutrition labelling is a potential method to encourage consumers to improve dietary behaviour. This systematic review and network meta-analysis ... -
Impact of fractional excretion of sodium on a single morning void urine collection as an estimate of 24-hour urine sodium.
(2019-12)The standard for assessing dietary sodium intake is to measure 24-hour urine sodium. On average, 93% of daily sodium intake is excreted over 24-hours. Expense and difficulties in obtaining complete 24-hour collections have ... -
The impact of providing blood to the scene of an accident on transfusion laboratory practice.
(2018-02)BACKGROUND: Haemorrhage is the leading cause of mortality during trauma. In 2012, London's Air Ambulance introduced Blood on Board (BOB), transfusing group O red cells (RBC) to trauma patients at the scene. OBJECTIVES: ... -
Impact of the 2003 to 2018 Population Salt Intake Reduction Program in England A Modeling Study
(Wolters Kluwer Health, Inc., 2021-03-01)The United Kingdom was among the first countries to introduce a salt reduction program in 2003 to reduce cardiovascular disease (CVD) incidence risk. Despite its initial success, the program has stalled recently and is yet ... -
The influence of anemia on clinical outcomes in venous thromboembolism: Results from GARFIELD-VTE.
(2021-07)INTRODUCTION: Clinical characteristics and outcomes of venous thromboembolism (VTE) patients with concomitant anemia are unclear. This study compares baseline characteristics, treatment patterns, and 24-month outcomes in ... -
Influence of Body Mass Index on Clinical Outcomes in Venous Thromboembolism: Insights from GARFIELD-VTE.
(2021-09-06)BACKGROUND: There is limited information on the influence of body mass index (BMI) on clinical outcomes in patients with venous thromboembolism (VTE). OBJECTIVES: Investigate the influence of BMI on baseline characteristics, ...