RSS 1.0Wolfson Institute of Preventive Medicine
The Wolfson Institute of Preventive Medicine is an internationally recognised centre for research and teaching and a part of Queen Mary’s medical faculty, Barts and The London School of Medicine and Dentistry. The Institute identifies the causes and methods of prevention of health conditions that lead to poor quality of life and premature death. These include cancer, cardiovascular disease, congenital malformations, psychiatric illnesses, neurologic diseases such as Parkinson’s, Dementia, and Multiple Sclerosis, and diseases caused by lifestyle factors such as tobacco use and diet.
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Centre for Cancer Prevention [1098]
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Centre for Psychiatry [792]
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Recent Submissions
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Maximising the acceptability of extended time intervals between screens in the NHS Cervical Screening Programme: An online experimental study
(SAGE Publications, 2021-09)Objective The NHS Cervical Screening Programme plans to increase the screening interval from 3 to 5 years for women aged 25–49 who test negative for human papillomavirus (HPV). This exploratory cross-sectional online ... -
Real-world persistence of multiple sclerosis disease-modifying therapies.
(John Wiley & Sons Ltd, 2024-04-03)BACKGROUND AND PURPOSE: Treatment persistence is the continuation of therapy over time. It reflects a combination of treatment efficacy and tolerability. We aimed to describe real-world rates of persistence on disease-modifying ... -
Short-term psychosocial outcomes of adding a non-contrast abdominal computed tomography (CT) scan to the thoracic CT within lung cancer screening.
(2024-05)OBJECTIVES: To evaluate psychological, social, and financial outcomes amongst individuals undergoing a non-contrast abdominal computed tomography (CT) scan to screen for kidney cancer and other abdominal malignancies ... -
Attitudes to multi-cancer early detection (MCED) blood tests for population-based screening: A qualitative study in Great Britain.
(2024-04)BACKGROUND: Trials are underway to test the clinical utility of multi-cancer early detection (MCED) blood tests for screening asymptomatic individuals. We sought to understand the acceptability of MCED blood test screening ... -
The oncological and reproductive outcomes of fertility-preserving treatments for stage 1 grade 1 endometrial carcinoma: a systematic review and meta-analysis.
(Taylor & Francis, 2023-12-21)INTRODUCTION: The number of patients desiring fertility-preserving treatment for endometrial cancer rather than standard surgical management continues to increase. OBJECTIVE: We aimed to evaluate the efficacies of ... -
Understanding lived experiences and perceptions of resilience in black and South Asian Muslim children living in East London: a qualitative study protocol.
(2024-04-10)INTRODUCTION: It is important to promote resilience in preadolescence; however, there is limited research on children's understandings and experiences of resilience. Quantitative approaches may not capture dynamic and ... -
Quality Appraisal in Systematic Literature Reviews of Studies Eliciting Health State Utility Values: Conceptual Considerations.
(Springer, 2024-03-29)BACKGROUND: The increasing number of studies that generate health state utility values (HSUVs) and the impact of HSUVs on cost-utility analyses make a robust tailored quality appraisal (QA) tool for systematic reviews of ... -
Patient-reported outcome measures for monitoring primary care patients with depression: the PROMDEP cluster RCT and economic evaluation.
(NIHR Journals Library, 2024-03)BACKGROUND: Guidelines on the management of depression recommend that practitioners use patient-reported outcome measures for the follow-up monitoring of symptoms, but there is a lack of evidence of benefit in terms of ... -
Short-term and medium-term clinical outcomes of multisystem inflammatory syndrome in children: a prospective observational cohort study.
(2024-01-04)BACKGROUND: Even though the incidence of Multisystem Inflammatory Syndrome in children (MIS-C) is decreasing cases are still reported across the world. Studying the consequences of MIS-C enhances our understanding of the ... -
Segmental ischemia and indocyanine green navigation: impact on perioperative parameters in laparoscopic vs. open partial nephrectomy
(2023-01-01)The aim of this study is to compare perioperative parameters of laparoscopic partial nephrectomy and open partial nephrectomy in renal tumor management, and to evaluate the effect of using novel method of indocyanine green ... -
BRCA awareness and testing experience in the UK Jewish population: a qualitative study
(BMJ Publishing Group, 04-04-2024)Background 1 in 40 UK Jewish individuals carry a pathogenic variant in BRCA1/BRCA2. Traditional testing criteria miss half of carriers, and so population genetic testing is being piloted for Jewish people in England. There ... -
Should I Take Aspirin? (SITA): RCT of a decision aid for cancer chemoprevention.
(2024-03-25)Background Australian guidelines recommend that all people aged 50-70 years old consider taking low-dose aspirin to reduce the risk of colorectal cancer (CRC). Aim To determine the effect of a consultation with a researcher ... -
Distinguishing emotional distress from mental disorder: A qualitative exploration of the Four-Dimensional Symptom Questionnaire (4DSQ).
(2024-03-18)BACKGROUND: Primary care clinicians see people experiencing the full range of mental health problems. Determining when symptoms reflect disorder is complex. The Four-Dimensional Symptom Questionnaire (4DSQ) uniquely ... -
Talking in primary care (TIP): protocol for a cluster-randomised controlled trial in UK primary care to assess clinical and cost-effectiveness of communication skills e-learning for practitioners on patients' musculoskeletal pain and enablement.
(2024-03-19)INTRODUCTION: Effective communication can help optimise healthcare interactions and patient outcomes. However, few interventions have been tested clinically, subjected to cost-effectiveness analysis or are sufficiently ...
