Show simple item record

dc.contributor.authorJovanovic, N
dc.contributor.authorFrancis, J
dc.contributor.authorMaric, NP
dc.contributor.authorArenliu, A
dc.contributor.authorBarjaktarov, S
dc.contributor.authorKulenovic, AD
dc.contributor.authorInjac, L
dc.contributor.authorFeng, Y
dc.contributor.authorNovotni, A
dc.date.accessioned2020-06-29T13:56:48Z
dc.date.available2020-06-29T13:56:48Z
dc.date.issued2019-09-04
dc.identifier.citationJovanovicet al. 2019. Implementing a psychosocial intervention DIALOG+ for patients with psychotic disorders in low and middle income countries in South Eastern Europe: protocol for a hybrid effectiveness-implementation cluster randomized clinical trial (IMPULSE). Global Psychiatry, 2 (2), https://doi.org/10.2478/gp-2019-0020en_US
dc.identifier.issn2451-4950
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/65289
dc.description.abstractPsychotic disorders have large treatment gap in low- and middle-income countries (LMICs) in South-Eastern Europe, where up to 45% of affected people do not receive care for their condition. This study will assess the implementation of a generic psychosocial intervention called DIALOG+ in mental health care services and its effectiveness at improving patients’ clinical and social outcomes.This is a protocol for a multi-country, pragmatic, hybrid effectiveness–implementation, cluster-randomised, clinical trial. The trial aims to recruit 80 clinicians and 400 patients across 5 South-Eastern European LMICs: Bosnia and Herzegovina, Kosovo*, Montenegro, Republic of North Macedonia and Serbia. Clusters are clinicians working with patients with psychosis, and each clinician will deliver the intervention to five patients. After patient baseline assessments, clinicians will be randomly assigned to either the DIALOG+ intervention or treatment as usual, with an allocation ratio of 1:1. The intervention will be delivered six times over 12 months during routine clinical meetings. TThe primary outcome measure is the quality of life at 12 months [Manchester Short Assessment of Quality of Life (MANSA)]; the secondary outcomes include mental health symptoms [Brief Psychiatric Rating Scale (BPRS), Clinical Assessment Interview for Negative Symptoms (CAINS), Brief Symptom Inventory (BSI)], satisfaction with services [Client Satisfaction Questionnaire (CSQ-8)] and economic costs at 12 months [based on Client Service Receipt Inventory (CSRI), EQ-5D-5L and Recovering Quality of Life (ReQOL-10)]. The study will assess the intervention fidelity and the experience of clinicians and patients’ about implementing DIALOG+ in real-life mental health care settings. In the health economic assessment, the incremental cost-effectiveness ratio is calculated with effectiveness measured by quality-adjusted life year. Data will also be collected on sustainability and reach to inform guidelines for potentially scaling up and implementing the intervention widely. Conclusion: The study is expected to generate new scientific knowledge on the treatment of people with psychosis in health care systems with limited resources. The learning from LMICs could potentially help other countries to expand the access to care and alleviate the suffering of patients with psychosis and their families.</jats:p> <jats:p>Trial registration: ISRCTN 11913964</jats:p></jats:sec>en_US
dc.description.sponsorshipThis study has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 779334.en_US
dc.language.isoenen_US
dc.publisherWalter de Gruyter GmbHen_US
dc.relation.ispartofGlobal Psychiatry
dc.rightsCC-NC ND
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectPsychiatryen_US
dc.subjectPsychological interventionen_US
dc.titleImplementing a psychosocial intervention DIALOG+ for patients with psychotic disorders in low and middle income countries in South Eastern Europe: protocol for a hybrid effectiveness-implementation cluster randomized clinical trial (IMPULSE)en_US
dc.typeArticleen_US
dc.rights.holder2019 Nikolina Jovanovic et al., published by Sciendo
dc.identifier.doi10.2478/gp-2019-0020
pubs.issue0en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume0en_US
dcterms.dateAccepted2019-09-28
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US
rioxxterms.funder.project483cf8e1-88a1-4b8b-aecb-8402672d45f8en_US


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

CC-NC ND
Except where otherwise noted, this item's license is described as CC-NC ND