Refining rodent models of spinal cord injury.
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Volume
328
Pagination
113273 - ?
Publisher
DOI
10.1016/j.expneurol.2020.113273
Journal
Experimental Neurology
Metadata
Show full item recordAbstract
This report was produced by an Expert Working Group (EWG) consisting of UK-based researchers, veterinarians and regulators of animal experiments with specialist knowledge of the use of animal models of spinal cord injury (SCI). It aims to facilitate the implementation of the Three Rs (Replacement, Reduction and Refinement), with an emphasis on refinement. Specific animal welfare issues were identified and discussed, and practical measures proposed, with the aim of reducing animal use and suffering, reducing experimental variability, and increasing translatability within this critically important research field.