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Determination of |Vub| using the lepton energy spectrum in events tagged with a fully reconstructed B meson
(2009)
We present measurements of partial branching fractions for the inclusive semileptonic decay
of B ! Xu` (` = e or ) leading to the determination of the CKM matrix element jVubj.
This analysis is based on a sample of ...
Systematic analysis of genomic alterations in prostate cancer
(2011)
Prostate cancer is the most common male cancer in Western countries. The genetic
mechanism underlying its initiation and progression is still unclear. The aim of this
project was to identify novel genomic changes in ...
Phylo-epidemiological and pathogenic diversity of Mycobacterium tuberculosis strains in London with implications for vaccine develpoment
(2010)
Approximately one-third of the global population is infected with tuberculosis causing
approximately 1.7 million deaths. Currently, the BCG vaccine is used to protect
against TB, but it cannot prevent primary infection ...
The relationship of human chorionic gonadotropin beta (hCGβ) expression and luteinizing hormone gene mutation (vLH) with prostate cancer in population groups of multi-ethnic origin
(2007)
Data have shown that Black men have the highest incidence and mortality from prostate cancer in the world. Even after adjusting for stage at diagnosis, black men have higher mortality rates than white men (Freedland, 2005). ...
Bayesian Design and Analysis of Small Multifactor Industrial Experiments
(2011)
Unreplicated two level fractional factorial designs are a common type of experimental
design used in the early stages of industrial experimentation. They allow considerable
information about the e ects of several factors ...
Identification of adenovirus E1A gene regions involved in chemosensitisation of prostate cancer cells
(2009)
Replication-selective adenoviruses are promising anti-cancer therapies
(virotherapy). Viruses can be engineered to selectively target cancer cells by
deleting viral genes involved in cell cycle regulation. These deletions ...
Rapid Access Chest Pain Clinics: characteristics and outcomes of patients from six centres
(2009)
Background Despite the widespread proliferation of rapid access chest pain clinics (RACPCs), there remain outstanding questions about their effectiveness. The aim of my thesis is to determine:
Aim 1) the variation in the ...
A 'philosophical storehouse': the life and afterlife of the Royal Society's repository
(2009)
In June 1781, the Royal Society’s repository was transferred to the British
Museum. Though ostensibly as a result of the limited space in the Royal Society’s
purpose-built accommodation at Somerset House, the Society ...
Investigation of distal repetitive sequences in the genus allium
(2009)
The telomere is a DNA/protein structure required to maintain the ends of linear chromosomes.
Usually the DNA component comprises a highly conserved tandemly repeated
minisatellite sequence. In most plants the minisatellite ...
Molecular genetic analysis in the hereditary vitreoretinopathies
(2010)
‘Hereditary vitreoretinopathy’ encompasses a group of inherited disorders characterized by an abnormal appearance to the vitreous gel of the eye. These conditions have a reputation among ophthalmologists for consisting ...