Browsing Centre for Oral Immunobiology and Regenerative Medicine by Title
Now showing items 81-100 of 558
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Cancer Cell Metabolism
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Cancer-associated cells release citrate to support tumour metastatic progression
(Life Science Alliance, 2021-03-23)Citrate is important for lipid synthesis and epigenetic regulation in addition to ATP production. We have previously reported that cancer cells import extracellular citrate via the pmCiC transporter to support their ... -
CD19(+)CD24(hi)CD38(hi) B Cells Maintain Regulatory T Cells While Limiting T(H)1 and T(H)17 Differentiation
(American Association for the Advancement of Science, 2013-02-20)The relevance of regulatory B cells in the maintenance of tolerance in healthy individuals or in patients with immune disorders remains understudied. In healthy individuals, CD19+ CD24hiCD38hi B cells suppress CD4+ CD25− ... -
A cell-based assay for the detection of neutralizing antibodies against alemtuzumab.
(2020-02-25)Aim: The humanized anti-CD52 monoclonal antibody alemtuzumab depletes lymphocytes and is currently used to treat relapsing multiple sclerosis. During treatment, anti-alemtuzumab antibodies may develop and reduce effective ... -
Cerebrovascular damage caused by the gut microbe/host co-metabolite <i>p</i> -cresol sulfate is prevented by blockade of the EGF receptor
(Taylor & Francis, 2024-11-24)The gut microbiota-brain axis has been associated with the pathogenesis of numerous disorders, but the mechanism(s) underlying these links are generally poorly understood. Accumulating evidence indicates the involvement ... -
Circulating NK cells and their subsets in Behçet's disease
(Wiley, 2017-05-01)Behçet's disease (BD) is an autoinflammatory, chronic relapsing/remitting disease of unknown aetiology with both innate and acquired immune cells implicated in disease pathogenesis. Peripheral blood natural killer (NK) ... -
Circulating NK cells and their subsets in Behçet’s Disease
(Wiley, 2017-02-06)Behçet’s Disease (BD) is an auto-inflammatory, chronic relapsing/remitting disease of unknown aetiology with both innate and acquired immune cells implicated in disease pathogenesis. Peripheral blood Natural Killer (NK) ...