Browsing Centre for Cell Biology and Cutaneous Research by Title
Now showing items 21-40 of 365
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ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells.
(2013-04)RAS mutations occur frequently in human cancer and activated RAS signalling contributes to tumour development and progression. Apart from its oncogenic effects on cell growth, active RAS has tumour-suppressive functions ... -
Association of arterial stiffness with single nucleotide polymorphism rs1333049 and metabolic risk factors
(2013)BACKGROUND: Increased arterial stiffness is a cardiovascular outcome of metabolic syndrome (MetS). The chromosome 9p21 locus has been identified as a major locus for risk of coronary artery disease (CAD). The single ...