Show simple item record

dc.contributor.authorMorgan, SEen_US
dc.contributor.authorWhite, SRen_US
dc.contributor.authorBullmore, ETen_US
dc.contributor.authorVértes, PEen_US
dc.description.abstractHuman brain networks based on neuroimaging data have already proven useful in characterizing both normal and abnormal brain structure and function. However, many brain disorders are neurodevelopmental in origin, highlighting the need to go beyond characterizing brain organization in terms of static networks. Here, we review the fast-growing literature shedding light on developmental changes in network phenotypes. We begin with an overview of recent large-scale efforts to map healthy brain development, and we describe the key role played by longitudinal data including repeated measurements over a long period of follow-up. We also discuss the subtle ways in which healthy brain network development can inform our understanding of disorders, including work bridging the gap between macroscopic neuroimaging results and the microscopic level. Finally, we turn to studies of three specific neurodevelopmental disorders that first manifest primarily in childhood and adolescence/early adulthood, namely psychotic disorders, attention-deficit/hyperactivity disorder, and autism spectrum disorder. In each case we discuss recent progress in understanding the atypical features of brain network development associated with the disorder, and we conclude the review with some suggestions for future directions.en_US
dc.format.extent754 - 766en_US
dc.relation.ispartofBiol Psychiatry Cogn Neurosci Neuroimagingen_US
dc.subjectAutism spectrum disorderen_US
dc.subjectNetwork neuroscienceen_US
dc.titleA Network Neuroscience Approach to Typical and Atypical Brain Development.en_US
dc.rights.holder© 2018 Society of Biological Psychiatry
pubs.notesNot knownen_US
pubs.notesAccepted version was uploaded on Apollo (Cambridge OA repository) within the 3 months period.en_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record