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dc.contributor.authorLorincz, A
dc.contributor.authorCastanon, A
dc.contributor.authorWey Lim, AW
dc.contributor.authorSasieni, P
dc.descriptionAuthor manuscript; published in final edited form as: Womens Health (Lond Engl). 2013 September; 9(5):. doi:10.2217/whe.13.48
dc.description.abstractHuman papillomavirus testing has been shown to be far more sensitive and robust in detecting cervical intraepithelial neoplasia 2 and above (and cervical intraepithelial neoplasia 3 and above) for cervical screening than approaches based on either cytology or visual inspection; however, there are a number of issues that need to be overcome if it is to substantially reduce the morbidity and mortality associated with cervical cancer at the population level. The two main issues are coverage (increasing the number of women who participate in screening) and the management of women who test positive for high-risk human papillomavirus. This article will review the potential for vaginal self-collection to improve coverage and the options for triage of high-risk human papillomavirus-positive women in high-resource and low-resource settings.
dc.format.extent443 - 452
dc.relation.ispartofWomens Health (Lond)
dc.subjectCervical Intraepithelial Neoplasia
dc.subjectCytological Techniques
dc.subjectDNA Methylation
dc.subjectDNA, Viral
dc.subjectGenes, p16
dc.subjectHuman papillomavirus 16
dc.subjectHuman papillomavirus 18
dc.subjectMass Screening
dc.subjectPapillomavirus Infections
dc.subjectRisk Factors
dc.subjectSensitivity and Specificity
dc.subjectTime Factors
dc.subjectVaginal Smears
dc.subjectWomen's Health
dc.titleNew strategies for human papillomavirus-based cervical screening.
dc.typeJournal Article
dc.relation.isPartOfWomens Health (Lond Engl)
dc.relation.isPartOfWomens Health (Lond)
dc.relation.isPartOfWomens Health (Lond)
pubs.organisational-group/Queen Mary University of London
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry/Wolfson Institute of Preventive Medicine
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry/Wolfson Institute of Preventive Medicine/Centre for Cancer Prevention
pubs.organisational-group/Queen Mary University of London/Impact Leads

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