Show simple item record

dc.contributor.authorHatemi, Gen_US
dc.contributor.authorChristensen, Ren_US
dc.contributor.authorBang, Den_US
dc.contributor.authorBodaghi, Ben_US
dc.contributor.authorCelik, AFen_US
dc.contributor.authorFortune, Fen_US
dc.contributor.authorGaudric, Jen_US
dc.contributor.authorGul, Aen_US
dc.contributor.authorKötter, Ien_US
dc.contributor.authorLeccese, Pen_US
dc.contributor.authorMahr, Aen_US
dc.contributor.authorMoots, Ren_US
dc.contributor.authorOzguler, Yen_US
dc.contributor.authorRichter, Jen_US
dc.contributor.authorSaadoun, Den_US
dc.contributor.authorSalvarani, Cen_US
dc.contributor.authorScuderi, Fen_US
dc.contributor.authorSfikakis, PPen_US
dc.contributor.authorSiva, Aen_US
dc.contributor.authorStanford, Men_US
dc.contributor.authorTugal-Tutkun, Ien_US
dc.contributor.authorWest, Ren_US
dc.contributor.authorYurdakul, Sen_US
dc.contributor.authorOlivieri, Ien_US
dc.contributor.authorYazici, Hen_US
dc.date.accessioned2018-11-19T10:16:30Z
dc.date.available2018-03-21en_US
dc.date.issued2018-06en_US
dc.date.submitted2018-08-28T16:04:47.067Z
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/51525
dc.description.abstractSeveral new treatment modalities with different mechanisms of action have been studied in patients with Behçet's syndrome (BS). The aim of the current effort was to update the recommendations in the light of these new data under the auspices of the European League Against Rheumatism (EULAR) Standing Committee for Clinical Affairs. A task force was formed that included BS experts from different specialties including internal medicine, rheumatology, ophthalmology, dermatology, neurology, gastroenterology, oral health medicine and vascular surgery, along with a methodologist, a health professional, two patients and two fellows in charge of the systematic literature search. Research questions were determined using a Delphi approach. EULAR standardised operating procedures was used as the framework. Results of the systematic literature review were presented to the task force during a meeting. The former recommendations were modified or new recommendations were formed after thorough discussions followed by voting. The recommendations on the medical management of mucocutaneous, joint, eye, vascular, neurological and gastrointestinal involvement of BS were modified; five overarching principles and a new recommendation about the surgical management of vascular involvement were added. These updated, evidence-based recommendations are intended to help physicians caring for patients with BS. They also attempt to highlight the shortcomings of the available clinical research with the aim of proposing an agenda for further research priorities.en_US
dc.description.sponsorshipThis project was funded by the European League Against Rheumatism.en_US
dc.format.extent808 - 818en_US
dc.languageengen_US
dc.relation.ispartofAnn Rheum Disen_US
dc.subjectanti-tnfen_US
dc.subjectbehcet’s diseaseen_US
dc.subjecttreatmenten_US
dc.title2018 update of the EULAR recommendations for the management of Behçet's syndrome.en_US
dc.typeArticle
dc.rights.holder© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
dc.identifier.doi10.1136/annrheumdis-2018-213225en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/29625968en_US
pubs.issue6en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume77en_US
dcterms.dateAccepted2018-03-21en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record