Now showing items 1-2 of 2

    • Novel Genetic Causes of Pituitary Adenomas. 

      Caimari, F; Korbonits, M (2016-10-15)
      Recently, a number of novel genetic alterations have been identified that predispose individuals to pituitary adenomas. Clinically relevant pituitary adenomas are relatively common, present in 0.1% of the general population. ...
    • Somatic USP8 mutations are frequent events in corticotroph tumor progression causing Nelson's tumor. 

      Pérez-Rivas, LG; Theodoropoulou, M; Puar, TH; Fazel, J; Stieg, MR; Ferraù, F; Assié, G; Gadelha, MR; Deutschbein, T; Fragoso, MC (2018-01)
      OBJECTIVE: Somatic mutations in the ubiquitin-specific protease 8 (USP8) gene are frequent in corticotroph tumors causing Cushing's disease (CD). Corticotroph tumor progression, the so-called Nelson's syndrome (NS), is a ...