Browsing Centre for Endocrinology by Title
Now showing items 251-270 of 552
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The kindlin family: functions, signaling properties and implications for human disease
(The Company of Biologists, 2016-01-01) -
Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation
(Springer Science and Business Media LLC, 2014-04) -
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin
<jats:p>Integrins require an activation step prior to ligand binding and signaling. How talin and kindlin contribute to these events in non-hematopoietic cells is poorly understood. Here we report that fibroblasts lacking ... -
Kindlin-3–mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells
(Rockefeller University Press, 2015-08-24)<jats:p>Hematopoietic stem cells (HSCs) generate highly dividing hematopoietic progenitor cells (HPCs), which produce all blood cell lineages. HSCs are usually quiescent, retained by integrins in specific niches, and become ... -
Laparoscopic adrenalectomy for phaeochromocytoma in the context of acute coronary syndrome
(Bioscientifica, 2023-11) -
Live Fast, Die Young?
(2023) -
Long-term outcome of partial P450 side-chain cleavage enzyme deficiency in three brothers: the importance of early diagnosis.
(2020-03)Objective: CYP11A1 mutations cause P450 side-chain cleavage (scc) deficiency, a rare form of congenital adrenal hyperplasia with a wide clinical spectrum. We detail the phenotype and evolution in a male sibship identified ...