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Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease.

Ng, SC; Benjamin, JL; McCarthy, NE; Hedin, CRH; Koutsoumpas, A; Plamondon, S; Price, CL; Hart, AL; Kamm, MA; Forbes, A;... (2011-10)

BACKGROUND: Altered intestinal dendritic cell (DC) function underlies dysregulated T-cell responses to bacteria in Crohn's disease (CD) but it is unclear whether composition of the intestinal microbiota impacts local DC ...