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M3C: Monte Carlo reference-based consensus clustering.
(2020-02-04)
Genome-wide data is used to stratify patients into classes for precision medicine using clustering algorithms. A common problem in this area is selection of the number of clusters (K). The Monti consensus clustering algorithm ...
B Cell Synovitis and Clinical Phenotypes in Rheumatoid Arthritis: Relationship to Disease Stages and Drug Exposure.
(2019-11-29)
OBJECTIVE: To define the relationship of synovial B cells to clinical phenotypes at different stages of disease evolution and drug exposure in rheumatoid arthritis (RA). METHODS: Synovial biopsy specimens and demographic ...
Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis.
(2020-04-01)
OBJECTIVES: IL-36 agonists are pro-inflammatory cytokines involved in the pathogenesis of psoriasis. However, their role in the pathogenesis of arthritis and treatment response to DMARDs in PsA remains uncertain. Therefore, ...
M3C: Monte Carlo reference-based consensus clustering
(bioRxiv, 2019-12-04)
Abstract: Genome-wide data is used to stratify patients into classes for precision medicine using clustering algorithms. A common problem in this area is selection of the number of clusters (K). The Monti consensus clustering ...
B CELL-RICH SYNOVITIS IN EARLY AND ESTABLISHED RHEUMATOID ARTHRITIS
(2020-04)
Meeting abstract P233 from British Society for Rheumatology Annual Conference 2020