Now showing items 61-70 of 70
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
(Nature Research (part of Springer Nature), 2017-12-22)
Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which ...
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
(American Heart Association, 2017-10-13)
Background— Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants ...
Genetics and genomics of systemic hypertension
© Springer International Publishing AG 2018. All rights are reserved. Since 2007 there has been substantial progress in mapping blood pressure genes, and large-scale genome-wide association studies now indicate over 400 ...