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In the eye of the storm: T cell behavior in the inflammatory microenvironment.
(2013)
Coordinated unfolding of innate and adaptive immunity is key to the development of protective immune responses. This functional integration occurs within the inflamed tissue, a microenvironment enriched with factors released ...
A novel role for syndecan-3 in angiogenesis.
(2013)
Syndecan-3 is one of the four members of the syndecan family of heparan sulphate proteoglycans and has been shown to interact with numerous growth factors via its heparan sulphate chains. The extracellular core proteins ...
Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA).
(2013)
INTRODUCTION: The present study aimed to explore a possible role for IL-21 producing Th-cells in the immunopathogenesis of granulomatosis with polyangiitis (GPA). METHODS: Peripheral blood from 42 GPA patients in remission ...
Acute Skeletal Muscle Wasting in Critical Illness
(American Medical Association, 2013-10-16)
Importance Survivors of critical illness demonstrate skeletal muscle wasting with associated functional impairment.
Objective To perform a comprehensive prospective characterization of skeletal muscle wasting, defining ...