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AIP mutations in young patients with acromegaly and the Tampico Giant: the Mexican experience

Ramirez-Renteria, C; Hernandez-Ramirez, LC; Portocarrero-Ortiz, L; Vargas, G; Melgar, V; Espinosa, E; Laura Espinosa-de-los-Monteros, A; Sosa, E; Gonzalez, B; Zuniga, S;... (2016-08)

Ghrelin

Mueller, TD; Nogueiras, R; Andermann, ML; Andrews, ZB; Anker, SD; Argente, J; Batterham, RL; Benoit, SC; Bowers, CY; Broglio, F;... (2015-06)

In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism

Salvatori, R; Radian, S; Diekmann, Y; Iacovazzo, D; David, A; Gabrovska, P; Grassi, G; Bussell, A-M; Stals, K; Weber, A;... (2017-09)

Outcomes of annual surveillance imaging in an adult and paediatric cohort of succinate dehydrogenase B mutation carriers

Tufton, N; Shapiro, L; Srirangalingam, U; Richards, P; Sahdev, A; Kumar, AV; McAndrew, L; Martin, L; Berney, D; Monson, J;... (2017-02)

Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland.

Hernández-Ramírez, LC; Morgan, RML; Barry, S; D'Acquisto, F; Prodromou, C; Korbonits, M (2018-02-06)

Despite the well-recognized role of loss-of-function mutations of the aryl hydrocarbon receptor interacting protein gene (AIP) predisposing to pituitary adenomas, the pituitary-specific function of this tumor suppressor ...

Metformin prevents metabolic side effects during systemic glucocorticoid treatment.

Seelig, E; Meyer, S; Timper, K; Nigro, N; Bally, M; Pernicova, I; Schuetz, P; Müller, B; Korbonits, M; Christ-Crain, M (2017-03)

OBJECTIVES: Patients receiving glucocorticoid treatment are prone to develop metabolic complications. In preclinical studies, metformin prevented the development of the metabolic syndrome during glucocorticoid excess. We ...

Pheochromocytoma Is Characterized by Catecholamine-Mediated Myocarditis, Focal and Diffuse Myocardial Fibrosis, and Myocardial Dysfunction

Ferreira, VM; Marcelino, M; Piechnik, SK; Marini, C; Karamitsos, TD; Ntusi, NAB; Francis, JM; Robson, MD; Arnold, JR; Mihai, R;... (2016-05-24)

Regulation of Aryl Hydrocarbon Receptor Interacting Protein (AIP) Protein Expression by MiR-34a in Sporadic Somatotropinomas

Denes, J; Kasuki, L; Trivellin, G; Colli, LM; Takiya, CM; Stiles, CE; Barry, S; de Castro, M; Gadelha, MR; Korbonits, M (2015-02-06)

Factors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first-generation somatostatin analogues: an immunohistochemical study

Iacovazzo, D; Carlsen, E; Lugli, F; Chiloiro, S; Piacentini, S; Bianchi, A; Giampietro, A; Mormando, M; Clear, AJ; Doglietto, F;... (2016-02)

MAFA missense mutation causes familial insulinomatosis and diabetes mellitus.

Iacovazzo, D; Flanagan, SE; Walker, E; Quezado, R; de Sousa Barros, FA; Caswell, R; Johnson, MB; Wakeling, M; Brändle, M; Guo, M;... (2018-01-30)

The β-cell-enriched MAFA transcription factor plays a central role in regulating glucose-stimulated insulin secretion while also demonstrating oncogenic transformation potential in vitro. No disease-causing MAFA variants ...