Now showing items 21-30 of 36
Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
(Oxford University Press, 2019-01-29)
An individual's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-alcohol interactions ...
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
(Nature Research (part of Springer Nature), 2018-04-09)
We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls of diverse ancestry, identifying 40 coding variant association signals (P < 2.2 × 10−7); of these, 16 map outside known risk-associated ...
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.
(Nature Publishing Group, 2019-01-24)
Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large consortia have identified more than 130 loci associated with QT interval, QRS duration, PR interval, and heart rate (RR ...