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    AuthorKorbonits, M (2)Mohiddin, SA (2)Wragg, A (2)Abbott, TEF (1)Akker, SA (1)Andrade, J (1)Archbold, RA (1)Assié, G (1)Aung, N (1)Bampoe, S (1)... View MoreSubject
    Adult (12)
    Cohort Studies (12)
    Humans (12)Female (11)Male (10)Middle Aged (8)Aged (7)Risk Factors (4)Aged, 80 and over (3)Genetic Predisposition to Disease (3)... View MoreDate Issued2023 (1)2021 (1)2019 (1)2018 (3)2017 (1)2016 (3)2015 (2)
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    Somatic USP8 mutations are frequent events in corticotroph tumor progression causing Nelson's tumor. 

    Pérez-Rivas, LG; Theodoropoulou, M; Puar, TH; Fazel, J; Stieg, MR; Ferraù, F; Assié, G; Gadelha, MR; Deutschbein, T; Fragoso, MC;... (2018-01)
    OBJECTIVE: Somatic mutations in the ubiquitin-specific protease 8 (USP8) gene are frequent in corticotroph tumors causing Cushing's disease (CD). Corticotroph tumor progression, the so-called Nelson's syndrome (NS), is a ...
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    Atypical risk factor profile and excellent long-term outcomes of young patients treated with primary percutaneous coronary intervention for ST-elevation myocardial infarction. 

    Rathod, KS; Jones, DA; Gallagher, S; Rathod, VS; Weerackody, R; Jain, AK; Mathur, A; Mohiddin, SA; Archbold, RA; Wragg, A;... (2016-02)
    INTRODUCTION: Several studies have examined the relationship between age and clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PPCI). The ...
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    Fracture Risk in Relation to Serum 25-Hydroxyvitamin D and Physical Activity: Results from the EPIC-Norfolk Cohort Study. 

    Julian, C; Lentjes, MAH; Huybrechts, I; Luben, R; Wareham, N; Moreno, LA; Khaw, K-T (2016)
    Vitamin D deficiency and physical inactivity have been associated with bone loss and fractures, but their combined effect has scarcely been studied either in younger or older adults. Therefore, we aimed to assess the ...
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    Ineffective and prolonged apical contraction is associated with chest pain and ischaemia in apical hypertrophic cardiomyopathy. 

    Stephenson, E; Monney, P; Pugliese, F; Malcolmson, J; Petersen, SE; Knight, C; Mills, P; Wragg, A; O'Mahony, C; Sekhri, N;... (2018-01-15)
    OBJECTIVES: To investigate the hypothesis that persistence of apical contraction into diastole is linked to reduced myocardial perfusion and chest pain. BACKGROUND: Apical hypertrophic cardiomyopathy (HCM) is defined by ...
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    Variants in the Mannose-binding Lectin Gene MBL2 do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort. 

    Mills, TC; Chapman, S; Hutton, P; Gordon, AC; Bion, J; Chiche, J-D; Holloway, PAH; Stüber, F; Garrard, CS; Hinds, CJ;... (2015-09-01)
    BACKGROUND: Sepsis is an increasingly common condition, which continues to be associated with unacceptably high mortality. A large number of association studies have investigated susceptibility to, or mortality from, sepsis ...
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    Inflammatory biomarker profiling in classical orthostatic hypotension: Insights from the SYSTEMA cohort. 

    Johansson, M; Ricci, F; Aung, N; Sutton, R; Melander, O; Fedorowski, A (2018-05-15)
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    Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases. 

    Ntalla, I; Kanoni, S; Zeng, L; Giannakopoulou, O; Danesh, J; Watkins, H; Samani, NJ; Deloukas, P; Schunkert, H; UK Biobank CardioMetabolic Consortium CHD Working Group (2019-06-18)
    BACKGROUND: The taxonomy of cardiovascular (CV) diseases is divided into a broad spectrum of clinical entities. Many such diseases coincide in specific patient groups and suggest shared predisposition. OBJECTIVES: This ...
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    Succinate Dehydrogenase B (SDHB)-Associated Bladder Paragangliomas. 

    Srirangalingam, U; Banerjee, A; Patki, P; Peters, J; George, E; Chew, SL; Kumar, VKA; Korbonits, M; Waterhouse, M; Druce, MR;... (2017-02)
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    Genetic and phenotypic characterization of complex hereditary spastic paraplegia. 

    Kara, E; Tucci, A; Manzoni, C; Lynch, DS; Elpidorou, M; Bettencourt, C; Chelban, V; Manole, A; Hamed, SA; Haridy, NA;... (2016-07)
    The hereditary spastic paraplegias are a heterogeneous group of degenerative disorders that are clinically classified as either pure with predominant lower limb spasticity, or complex where spastic paraplegia is complicated ...
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    Incidence of accidental awareness during general anaesthesia in obstetrics: a multicentre, prospective cohort study. 

    Odor, PM; Bampoe, S; Lucas, DN; Moonesinghe, SR; Andrade, J; Pandit, JJ; Pan-London Peri-operative Audit and Research Network (PLAN), for the DREAMY Investigators Group (2021-06)
    General anaesthesia for obstetric surgery has distinct characteristics that may contribute towards a higher risk of accidental awareness during general anaesthesia. The primary aim of this study was to investigate the ...
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