Now showing items 1-5 of 5
Fatal Carney Complex in Siblings Due to De Novo Large Gene Deletion.
Context: Carney complex (CNC) is a rare multiple neoplasia syndrome involving cardiac, endocrine, neural, and cutaneous tumors and a variety of pigmented skin lesions. CNC can be inherited as an autosomal dominant trait, ...
Metformin prevents metabolic side effects during systemic glucocorticoid treatment.
OBJECTIVES: Patients receiving glucocorticoid treatment are prone to develop metabolic complications. In preclinical studies, metformin prevented the development of the metabolic syndrome during glucocorticoid excess. We ...
Social, educational and vocational outcomes in patients with childhood-onset and young-adult-onset growth hormone deficiency.
OBJECTIVE: Hypopituitarism diagnosed in childhood, adolescence and young adulthood has the potential to affect growth and somatic development. Less is known about the impact of such a diagnosis on other aspects of development. ...
Renin-Angiotensin System Blockade Improves Cardiac Indices in Acromegaly Patients.
Blockade of the angiotensin-renin system, with angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs), has been shown to improve cardiac outcomes following myocardial infarction and delay ...