Now showing items 1-5 of 5
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
(Springer Nature, 2019-01-07)
Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking ...
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
(Nature Research (part of Springer Nature), 2019-02-18)
Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted ...
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.
(Nature Publishing Group, 2019-01-24)
Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large consortia have identified more than 130 loci associated with QT interval, QRS duration, PR interval, and heart rate (RR ...
Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease.
(Springer Nature, 2019-03-27)
There is evidence that lower height is associated with a higher risk of coronary artery disease (CAD) and increased risk of type 2 diabetes (T2D). It is not clear though whether these associations are causal, direct or ...