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Macimorelin as a Diagnostic Test for Adult GH Deficiency

Garcia, JM; Biller, BMK; Korbonits, M; Popovic, V; Luger, A; Strasburger, CJ; Chanson, P; Medic-Stojanoska, M; Schopohl, J; Zakrzewska, A;... (2018-08)

In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism

Salvatori, R; Radian, S; Diekmann, Y; Iacovazzo, D; David, A; Gabrovska, P; Grassi, G; Bussell, A-M; Stals, K; Weber, A;... (2017-09)

From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal.

Asa, SL; Casar-Borota, O; Chanson, P; Delgrange, E; Earls, P; Ezzat, S; Grossman, A; Ikeda, H; Inoshita, N; Karavitaki, N;... (2017-04)

The classification of neoplasms of adenohypophysial cells is misleading because of the simplistic distinction between adenoma and carcinoma, based solely on metastatic spread and the poor reproducibility and predictive ...

MAFA missense mutation causes familial insulinomatosis and diabetes mellitus.

Iacovazzo, D; Flanagan, SE; Walker, E; Quezado, R; de Sousa Barros, FA; Caswell, R; Johnson, MB; Wakeling, M; Brändle, M; Guo, M;... (2018-01-30)

The β-cell-enriched MAFA transcription factor plays a central role in regulating glucose-stimulated insulin secretion while also demonstrating oncogenic transformation potential in vitro. No disease-causing MAFA variants ...

Sensitivity and specificity of the macimorelin test for diagnosis of AGHD.

Garcia, JM; Ross, A; Biller, BMK; Korbonits, M; Popovic, V; Luger, A; Strasburger, CJ; Chanson, P; Swerdloff, R; Wang, C;... (2020-12-01)

OBJECTIVE: The macimorelin test is approved for the diagnosis of adult growth hormone deficiency (AGHD) based on its efficacy vs the insulin tolerance test (ITT). Macimorelin has a significant advantage over ITT in avoiding ...

Pituitary Neoplasm Nomenclature Workshop: Does Adenoma Stand the Test of Time?

Ho, K; Fleseriu, M; Kaiser, U; Salvatori, R; Brue, T; Lopes, MB; Kunz, P; Molitch, M; Camper, SA; Gadelha, M;... (2021-03-01)

The WHO Classification of Endocrine Tumours designates pituitary neoplasms as adenomas. A proposed nomenclature change to pituitary neuroendocrine tumors (PitNETs) has been met with concern by some stakeholder groups. The ...

SAT-428 Effect of Age, Body Mass Index, and Sex on the Performance of Macimorelin for the Diagnosis of Adult Growth Hormone Deficiency: A Post Hoc Analysis

Garcia, J; Biller, BM; Korbonits, M; Popovic-Brkic, V; Luger, A; Strasburger, C; Chanson, P; Swerdloff, R; Wang, C; Fleming, RR;... (2019-04-15)

Polymorphism or mutation? - The role of the R304Q missense AIP mutation in the predisposition to pituitary adenoma

Mothojakan, NB; Ferrau, F; Dang, MN; Barlier, A; Chanson, P; Occhi, G; Daly, AF; Schofl, C; Dal, J; Gadelha, MR;... (2016-10-14)

OR32-4 Diagnostic Performance of Macimorelin vs the Insulin Tolerance Test (ITT) in 140 Patients at Varying Growth Hormone (GH) Cutpoints: A Post Hoc Analysis

Garcia, J; Biller, B; Korbonits, M; Popovic-Brkic, V; Luger, A; Strasburger, C; Chanson, P; Swerdloff, R; Wang, C; Fleming, RR;... (2019-04-15)

Pituitary MRI Features in Acromegaly Resulting From Ectopic GHRH Secretion From a Neuroendocrine Tumor: Analysis of 30 Cases (vol 107, pg e3313, 2022)

Potorac, I; Bonneville, J-F; Daly, AF; de Herder, W; Fainstein-Day, P; Chanson, P; Korbonits, M; Cordido, F; Lamback, EB; Abid, M;... (2022)