Search
Now showing items 1-6 of 6
Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland.
(2018-02-06)
Despite the well-recognized role of loss-of-function mutations of the aryl hydrocarbon receptor interacting protein gene (AIP) predisposing to pituitary adenomas, the pituitary-specific function of this tumor suppressor ...
Sporadic pituitary adenomas: the role of germline mutations and recommendations for genetic screening.
(2017-03)
INTRODUCTION: Although most pituitary adenomas occur sporadically, these common tumors can present in a familial setting in approximately 5% of cases. Germline mutations in several genes with autosomal dominant (AIP, MEN1, ...
Circulating aryl hydrocarbon receptor-interacting protein (AIP) is independent of GH secretion.
(2019-04)
Background: Aryl hydrocarbon receptor-interacting protein (AIP) is evolutionarily conserved and expressed widely throughout the organism. Loss-of-function AIP mutations predispose to young-onset pituitary adenomas. AIP ...
Genetics of Acromegaly and Gigantism.
(MDPI, 2021-03-29)
Growth hormone (GH)-secreting pituitary tumours represent the most genetically determined pituitary tumour type. This is true both for germline and somatic mutations. Germline mutations occur in several known genes (AIP, ...