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Detection of HER2 amplification in circulating free DNA in patients with breast cancer.

Page, K; Hava, N; Ward, B; Brown, J; Guttery, DS; Ruangpratheep, C; Blighe, K; Sharma, A; Walker, RA; Coombes, RC;... (2011-04-12)

BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in 20-25% of breast cancers. This study investigated circulating free DNA (cfDNA) for detection of HER2 gene amplification in ...