Browsing William Harvey Research Institute by Title

A zebrafish forward genetic screen identifies an indispensable threonine residue in the kinase domain of PRKD2

Giardoglou, P; Bournele, D; Park, M; Kanoni, S; Dedoussis, GV; Steinberg, SF; Deloukas, P; Beis, D (2021)

A zebrafish model of AIP loss of function

Wang, X; Leggieri, A; Anagianni, S; Brennan, CH; Korbonits, M

ZILEBESIRAN AS ADD-ON THERAPY IN PATIENTS WITH HYPERTENSION INADEQUATELY CONTROLLED WITH A STANDARD ANTIHYPERTENSIVE MEDICATION: EFFICACY AND SAFETY RESULTS FROM THE KARDIA-2 STUDY

Saxena, M; Aswad, A; Badariene, J; Kazi, F; Karns, AD; Neutel, JM; Park, W; Stiglitz, D; Makarova, N; Havasi, A (Wolters Kluwer, 2024-05)

Zinc-mediated inhibition of soluble epoxide hydrolase promotes pulmonary hypertension

de Jesus, DS; Buffonge, S; Abis, G; Buccafusca, R; Baliga, R; Warren, HR; Hobbs, A; Ruppert, C; Weiss, A; Schermuly, RT (Elsevier, 2024-11-14)

A Zn2+-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels

Varela, L; Hendry, AC; Cassar, J; Martin-Escolano, R; Cantoni, D; Ossa, F; Edwards, JC; Abdul-Salam, V; Ortega-Roldan, JL (2022)

β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte Homeostasis.

Hussain, MT; Austin-Williams, S; Wright, TD; Dhawan, UK; Pinto, AL; Cooper, D; Norling, LV (MDPI, 2024-04-26)

Osteoarthritis (OA) is the most prevalent age-related degenerative disorder, which severely reduces the quality of life of those affected. Whilst management strategies exist, no cures are currently available. Virtually all ...