Browsing William Harvey Research Institute by Title

Wall shear stress and pressure patterns in aortic stenosis patients with and without aortic dilation captured by high-performance image-based computational fluid dynamics.

Zolfaghari, H; Andiapen, M; Baumbach, A; Mathur, A; Kerswell, RR (2023-10)

Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate to severe AS, ...

Wall shear stress estimated by 3D-QCA can predict cardiovascular events in lesions with borderline negative fractional flow reserve

Tufaro, V; Safi, H; Torii, R; Koo, B-K; Kitslaar, P; Ramasamy, A; Mathur, A; Jones, DA; Bajaj, R; Erdogan, E (2021)

Wandering pathways in the regulation of innate immunity and inflammation

Mantovani, A (2017-12)

Ward monitoring 4.0: real-time metabolic insights from continuous glucose monitoring into perioperative organ dysfunction.

Janssen, H; Jhanji, S; Oliver, NS; Ackland, GL; GlucoVITAL Investigators (2024-03-05)

The now-routine clinical deployment of continuous glucose monitoring has demonstrated benefit in real-world settings. We make the case that continuous glucose monitoring can help re-examine, at scale, the role that (stress) ...

Weather, day length and physical activity in older adults: Cross-sectional results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Norfolk Cohort.

Wu, Y-T; Luben, R; Wareham, N; Griffin, S; Jones, AP (2017)

BACKGROUND: A wide range of environmental factors have been related to active ageing, but few studies have explored the impact of weather and day length on physical activity in older adults. We investigate the cross-sectional ...

What are small, medium and large effect sizes for exercise treatments of tendinopathy? A systematic review and meta-analysis

Swinton, PA; Shim, JSC; Pavlova, AV; Moss, R; Maclean, C; Brandie, D; Mitchell, L; Greig, L; Parkinson, E; Brown, VT (2023)

What factors affect implementation of early rehabilitation into intensive care unit practice? A qualitative study with clinicians

Parry, SM; Remedios, L; Denehy, L; Knight, LD; Beach, L; Rollinson, TC; Berney, S; Puthucheary, ZA; Morris, P; Granger, CL (2017-04)

What outcomes have been reported on patients following open lower limb fracture, and how have they been measured?

Aquilina, AL; Claireaux, H; Aquilina, CO; Tutton, E; Fitzpatrick, R; Costa, ML; Griffin, XL (2023)

Whole blood transcriptomic profiling identifies molecular pathways related to cardiovascular mortality in heart failure

Nath, M; Romaine, SPR; Koekemoer, A; Hamby, S; Webb, TR; Nelson, CP; Castellanos-Uribe, M; Papakonstantinou, M; Anker, SD; Lang, CC (2022)

Whole Exome Sequencing can Identify Defects not Detected by Candidate Gene Sequencing in Patients with Short Stature and Features of Growth Hormone Insensitivity (GHI)

Shapiro, L; Savage, M; Davies, K; Metherell, L; Storr, H (2016)

Whole exome sequencing identifies deleterious rare variants in CCDC141 in familial self-limited delayed puberty

Saengkaew, T; Ruiz-Babot, G; David, A; Mancini, A; Mariniello, K; Cabrera, CP; Barnes, MR; Dunkel, L; Guasti, L; Howard, SR (2021)

Whole genome sequence analysis suggests intratumoral heterogeneity in dissemination of breast cancer to lymph nodes.

Blighe, K; Kenny, L; Patel, N; Guttery, DS; Page, K; Gronau, JH; Golshani, C; Stebbing, J; Coombes, RC; Shaw, JA (2014)

BACKGROUND: Intratumoral heterogeneity may help drive resistance to targeted therapies in cancer. In breast cancer, the presence of nodal metastases is a key indicator of poorer overall survival. The aim of this study was ...

The whole truth and nothing but the truth: the need for full reporting of randomised trials.

Pearse, RM (2015)

The use of cardiac output monitoring to guide fluid and inotropic therapy in surgical patients has remained a controversial topic for more than 40 years. The reasons for this are numerous and complex, but key amongst them ...

Whole-body vibration decreases delayed onset muscle soreness following eccentric exercise in elite hockey players: a randomised controlled trial

Akehurst, H; Grice, JE; Angioi, M; Morrissey, D; Migliorini, F; Maffulli, N (2021)

Whole-exome sequencing gives additional benefits compared to candidate gene sequencing in the molecular diagnosis of children with growth hormone or IGF-1 insensitivity

Shapiro, L; Chatterjee, S; Ramadan, DG; Davies, KM; Savage, MO; Metherell, LA; Storr, HL (2017-12)

Whole-exome sequencing in the differential diagnosis of primary adrenal insufficiency in children

Chan, LF; Campbell, DC; Novoselova, TV; Clark, AJL; Metherell, LA (2016-08-05)

Whole-genome sequence-based analysis of thyroid function

Taylor, PN; Porcu, E; Chew, S; Campbell, PJ; Traglia, M; Brown, SJ; Mullin, BH; Shihab, HA; Min, J; Walter, K (2015-03)

Widespread uptake of the Human Phenotype Ontology (HPO) in the National Health Service (NHS) in England as part of the 100,000 Genomes Project

Thomas, ERA; Devereau, A; Brittain, H; Tucci, A; Ryten, M; Smedley, D; Rendon, A; Caulfield, MJ; Scott, RH (2019-07)

Will ABSORB III change my practice? Everolimus-eluting bioresorbable scaffolds for coronary artery disease

Cook, S; Nef, H; Capodanno, D; Tamburino, C; Baumbach, A (2016-08)

Will Genetic Data Significantly Change Cardiovascular Risk Prediction in Daily Practice?

Young, WJ; Ramirez, J; Van Duijvenboden, S; Tinker, A; Lambiase, PD; Munroe, PB; Orini, M (2020-09-13)

© 2020 Creative Commons; the authors hold their copyright. Precision medicine has been heralded as an opportunity to improve risk prediction, driven significantly by an increasing availability of genetic data. Genetic ...